4ago: Difference between revisions

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'''Unreleased structure'''
[[Image:4ago.jpg|left|200px]]


The entry 4ago is ON HOLD
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{{STRUCTURE_4ago|  PDB=4ago |  SCENE=  }}


Authors: Joerger, A.C., Wilcken, R., Fersht, A.R., Boeckler, F.M.
===Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan5174===


Description: Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan5174
 
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{{ABSTRACT_PUBMED_17015838}}
 
==About this Structure==
[[4ago]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AGO OCA].
 
==Reference==
<ref group="xtra">PMID:017015838</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Boeckler, F M.]]
[[Category: Fersht, A R.]]
[[Category: Joerger, A C.]]
[[Category: Wilcken, R.]]
[[Category: Acetylene linker]]
[[Category: Apoptosis]]
[[Category: Cancer mutation]]
[[Category: Cell cycle]]
[[Category: Halogen bonding]]
[[Category: Protein stabilization]]
[[Category: Small-molecule drug]]
[[Category: Surface crevice]]
[[Category: Transcription]]
[[Category: Zinc binding]]

Revision as of 10:51, 21 March 2012

File:4ago.jpg

Template:STRUCTURE 4ago

Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan5174Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan5174

Template:ABSTRACT PUBMED 17015838

About this StructureAbout this Structure

4ago is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Joerger AC, Ang HC, Fersht AR. Structural basis for understanding oncogenic p53 mutations and designing rescue drugs. Proc Natl Acad Sci U S A. 2006 Oct 10;103(41):15056-61. Epub 2006 Oct 2. PMID:17015838

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