3uza: Difference between revisions

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'''Unreleased structure'''
[[Image:3uza.jpg|left|200px]]


The entry 3uza is ON HOLD until Paper Publication
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{{STRUCTURE_3uza|  PDB=3uza  |  SCENE=  }}


Authors: Congreve, M., Andrews, S.P., Dore, A.S., Hollenstein, K., Hurrell, E., Langmead, C.J., Mason, J.S., Ng, I.W., Tehan, B., Zhukov, A., Weir, M., Marshall, F.H.
===Thermostabilised Adenosine A2A receptor in complex with 6-(2,6-Dimethylpyridin-4-yl)-5-phenyl-1,2,4-triazin-3-amine===


Description: Thermostabilised Adenosine A2A Receptor in complex with compound 4G
 
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{{ABSTRACT_PUBMED_22220592}}
 
==About this Structure==
[[3uza]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UZA OCA].
 
==Reference==
<ref group="xtra">PMID:022220592</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Andrews, S P.]]
[[Category: Congreve, M.]]
[[Category: Dore, A S.]]
[[Category: Hollenstein, K.]]
[[Category: Hurrell, E.]]
[[Category: Langmead, C J.]]
[[Category: Marshall, F H.]]
[[Category: Mason, J S.]]
[[Category: Ng, I W.]]
[[Category: Tehan, B.]]
[[Category: Weir, M.]]
[[Category: Zhukov, A.]]
[[Category: 7tm]]
[[Category: G-protein]]
[[Category: Gpcr]]
[[Category: Membrane protein]]
[[Category: Signaling protein]]

Revision as of 10:39, 21 March 2012

File:3uza.jpg

Template:STRUCTURE 3uza

Thermostabilised Adenosine A2A receptor in complex with 6-(2,6-Dimethylpyridin-4-yl)-5-phenyl-1,2,4-triazin-3-amineThermostabilised Adenosine A2A receptor in complex with 6-(2,6-Dimethylpyridin-4-yl)-5-phenyl-1,2,4-triazin-3-amine

Template:ABSTRACT PUBMED 22220592

About this StructureAbout this Structure

3uza is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Congreve M, Andrews SP, Dore AS, Hollenstein K, Hurrell E, Langmead CJ, Mason JS, Ng IW, Tehan B, Zhukov A, Weir M, Marshall FH. Discovery of 1,2,4-Triazine Derivatives as Adenosine A(2A) Antagonists using Structure Based Drug Design. J Med Chem. 2012 Mar 8;55(5):1898-903. Epub 2012 Jan 27. PMID:22220592 doi:10.1021/jm201376w

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