3s54: Difference between revisions

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'''Unreleased structure'''
[[Image:3s54.jpg|left|200px]]


The entry 3s54 is ON HOLD until Paper Publication
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{{STRUCTURE_3s54|  PDB=3s54  |  SCENE=  }}


Authors: Tie, Y.-F., Wang, Y.-F., Weber, I.T.
===HIV-1 protease triple mutants V32I, I47V, V82I with antiviral drug darunavir in space group P21212===


Description: HIV-1 protease triple mutants V32I, I47V, V82I with antiviral drug darunavir in space group P21212
 
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{{ABSTRACT_PUBMED_22238126}}
 
==About this Structure==
[[3s54]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S54 OCA].
 
==Reference==
<ref group="xtra">PMID:022238126</ref><references group="xtra"/>
[[Category: HIV-1 retropepsin]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Tie, Y F.]]
[[Category: Wang, Y F.]]
[[Category: Weber, I T.]]
[[Category: Aspartic protease]]
[[Category: Darunavir]]
[[Category: Drug resistance]]
[[Category: Hiv/aid]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Molecular recognition]]

Revision as of 10:37, 21 March 2012

File:3s54.jpg

Template:STRUCTURE 3s54

HIV-1 protease triple mutants V32I, I47V, V82I with antiviral drug darunavir in space group P21212HIV-1 protease triple mutants V32I, I47V, V82I with antiviral drug darunavir in space group P21212

Template:ABSTRACT PUBMED 22238126

About this StructureAbout this Structure

3s54 is a 2 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Tie Y, Wang YF, Boross PI, Chiu TY, Ghosh AK, Tozser J, Louis JM, Harrison RW, Weber IT. Critical differences in HIV-1 and HIV-2 protease specificity for clinical inhibitors. Protein Sci. 2012 Mar;21(3):339-50. doi: 10.1002/pro.2019. Epub 2012 Jan 24. PMID:22238126 doi:10.1002/pro.2019

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