Interface analysis servers: Difference between revisions
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*The buried and interfacial areas are not affected by the distance specified when submitting the job. | *The buried and interfacial areas are not affected by the distance specified when submitting the job. | ||
* | *Note that the ''Table of minimum distances'' lists only the minimum interatomic distance for each pair of residues, not all interatomic distances. The list of ''all'' can be obtained by clicking ''Open table'' under ''Distance table''. However it is not filterable or sortable at the time of this writing (March, 2012). | ||
==References== | ==References== | ||
<references /> | <references /> | ||
Revision as of 01:32, 3 March 2012
The purpose of this article is to list and evaluate servers that analyze interfaces within molecular models, such as protein-protein, DNA-protein, RNA-protein, and ligand-protein interfaces.
COCOMAPSCOCOMAPS
COCOMAPS[1] analyzes and visualizes interfaces in biological complexes (such as protein-protein, protein-DNA and protein-RNA complexes). The interface(s) to analyze are specified with the chain identifiers in the PDB file. Output includes three different contact maps, as well as tables reporting detailed information about the interacting residues (defined on the basis of a cut-off distance that can be customized by the user), the residues at the interfaces (defined on the basis of the buried surface upon complex formation), the inter-molecular H-bonds, the buried area, and the interface areas (both as Å2 and percentages).
CommentsComments
- The buried and interfacial areas are not affected by the distance specified when submitting the job.
- Note that the Table of minimum distances lists only the minimum interatomic distance for each pair of residues, not all interatomic distances. The list of all can be obtained by clicking Open table under Distance table. However it is not filterable or sortable at the time of this writing (March, 2012).
ReferencesReferences
- ↑ Vangone A, Spinelli R, Scarano V, Cavallo L, Oliva R. COCOMAPS: a web application to analyze and visualize contacts at the interface of biomolecular complexes. Bioinformatics. 2011 Oct 15;27(20):2915-6. doi: 10.1093/bioinformatics/btr484., Epub 2011 Aug 27. PMID:21873642 doi:http://dx.doi.org/10.1093/bioinformatics/btr484