4dkt: Difference between revisions

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'''Unreleased structure'''
[[Image:4dkt.jpg|left|200px]]


The entry 4dkt is ON HOLD until sometime in the future
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{{STRUCTURE_4dkt|  PDB=4dkt  |  SCENE=  }}


Authors: Jones, JE, Slack, JL, Fang, P., Zhang, X., Subramanian, V., Causey, CP, Coonrod, SA, Guo, M., Thompson, PR
===Crystal structure of human peptidylarginine deiminase 4 in complex with N-acetyl-L-threonyl-L-alpha-aspartyl-N5-[(1E)-2-fluoroethanimidoyl]-L-ornithinamide===


Description: Synthesis and Screening of a Haloacetamidine Containing Library To Identify PAD4 Selective Inhibitors
 
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{{ABSTRACT_PUBMED_22004374}}
 
==About this Structure==
[[4dkt]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DKT OCA].
 
==Reference==
<ref group="xtra">PMID:022004374</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Protein-arginine deiminase]]
[[Category: Causey, C P.]]
[[Category: Coonrod, S A.]]
[[Category: Fang, P.]]
[[Category: Guo, M.]]
[[Category: Jones, J E.]]
[[Category: Slack, J L.]]
[[Category: Subramanian, V.]]
[[Category: Thompson, P R.]]
[[Category: Zhang, X.]]
[[Category: Alpha/beta-propeller]]
[[Category: Arginine citrullination]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Immunoglobulin-like]]
[[Category: Post-translational]]

Revision as of 11:51, 29 February 2012

File:4dkt.jpg

Template:STRUCTURE 4dkt

Crystal structure of human peptidylarginine deiminase 4 in complex with N-acetyl-L-threonyl-L-alpha-aspartyl-N5-[(1E)-2-fluoroethanimidoyl]-L-ornithinamideCrystal structure of human peptidylarginine deiminase 4 in complex with N-acetyl-L-threonyl-L-alpha-aspartyl-N5-[(1E)-2-fluoroethanimidoyl]-L-ornithinamide

Template:ABSTRACT PUBMED 22004374

About this StructureAbout this Structure

4dkt is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Jones JE, Slack JL, Fang P, Zhang X, Subramanian V, Causey CP, Coonrod SA, Guo M, Thompson PR. Synthesis and screening of a haloacetamidine containing library to identify PAD4 selective inhibitors. ACS Chem Biol. 2012 Jan 20;7(1):160-5. Epub 2011 Oct 21. PMID:22004374 doi:10.1021/cb200258q

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