ATP Phosphoribosyl Transferase: Difference between revisions
No edit summary |
Michal Harel (talk | contribs) No edit summary |
||
| Line 1: | Line 1: | ||
=='''HisG – ATP Phosphoribosyl Transferase'''== | =='''HisG – ATP Phosphoribosyl Transferase'''== | ||
<applet load='1nh8' size=' | <applet load='1nh8' size='400' frame='true' align='right' caption='HisG with histidine and AMP bound, [[1nh8]]' /> | ||
ATP Phosphoribosyl transferase (ATP-PRTase) (EC 2.4.2.17), also called HisG, belongs to the enzyme super family, phosphoribosyl transferases (PRTases) and the glycosyltransferases family. It catalyzes the reversible condensation of 5-phosphoribosyl-α-1-pyrophosphate (PRPP) with ATP, yielding N’-5’-phosphoribosyl-ATP (PR-ATP) and inorganic pyrophosphate (PPi). | '''ATP Phosphoribosyl transferase''' (ATP-PRTase) (EC 2.4.2.17), also called HisG, belongs to the enzyme super family, phosphoribosyl transferases (PRTases) and the glycosyltransferases family. It catalyzes the reversible condensation of 5-phosphoribosyl-α-1-pyrophosphate (PRPP) with ATP, yielding N’-5’-phosphoribosyl-ATP (PR-ATP) and inorganic pyrophosphate (PPi). | ||
5-phosphoribosyl-α-1-pyrophosphate + ATP = N’-5’-phosphoribosyl-ATP + pyrophosphate. | 5-phosphoribosyl-α-1-pyrophosphate + ATP = N’-5’-phosphoribosyl-ATP + pyrophosphate. | ||