4a6l: Difference between revisions

Revision as of 09:35, 25 January 2012

4a6l is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

↑ Liang G, Aldous S, Merriman G, Levell J, Pribish J, Cairns J, Chen X, Maignan S, Mathieu M, Tsay J, Sides K, Rebello S, Whitely B, Morize I, Pauls HW. Structure-based library design and the discovery of a potent and selective mast cell beta-tryptase inhibitor as an oral therapeutic agent. Bioorg Med Chem Lett. 2012 Jan 15;22(2):1049-54. Epub 2011 Dec 7. PMID:22192588 doi:10.1016/j.bmcl.2011.11.119

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-'''Unreleased structure'''
+[[Image:4a6l.jpg|left|200px]]
-The entry 4a6l is ON HOLD  until Paper Publication
+<!--
+The line below this paragraph, containing "STRUCTURE_4a6l", creates the "Structure Box" on the page.
+You may change the PDB parameter (which sets the PDB file loaded into the applet)
+or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+or leave the SCENE parameter empty for the default display.
+-->
+{{STRUCTURE_4a6l|  PDB=4a6l  |  SCENE=  }}
-Authors: Mathieu, M., Maignan, S.
+===beta-tryptase inhibitor===
-Description: beta-tryptase inhibitor
+<!--
+The line below this paragraph, {{ABSTRACT_PUBMED_22192588}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 22192588 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_22192588}}
+==About this Structure==
+[[4a6l]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A6L OCA].
+==Reference==
+<ref group="xtra">PMID:022192588</ref><references group="xtra"/>
+[[Category: Homo sapiens]]
+[[Category: Tryptase]]
+[[Category: Maignan, S.]]
+[[Category: Mathieu, M.]]
+[[Category: Hydrolase]]
+[[Category: Inhibitor]]