5cox: Difference between revisions
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[[Image:5cox.gif|left|200px]]<br /><applet load="5cox" size=" | [[Image:5cox.gif|left|200px]]<br /><applet load="5cox" size="350" color="white" frame="true" align="right" spinBox="true" | ||
caption="5cox, resolution 3.0Å" /> | caption="5cox, resolution 3.0Å" /> | ||
'''UNINHIBITED MOUSE CYCLOOXYGENASE-2 (PROSTAGLANDIN SYNTHASE-2)'''<br /> | '''UNINHIBITED MOUSE CYCLOOXYGENASE-2 (PROSTAGLANDIN SYNTHASE-2)'''<br /> | ||
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==About this Structure== | ==About this Structure== | ||
5COX is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] with NAG and HEM as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Prostaglandin-endoperoxide_synthase Prostaglandin-endoperoxide synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.99.1 1.14.99.1] Known structural/functional Sites: <scene name='pdbsite=ACE:SER 530 Is Acetylated By Aspirin (An Acetyl Group Is Cov ...'>ACE</scene>, <scene name='pdbsite=CAT:TYR 385 Is Believed To Be The Amino Acid That Abstracts ...'>CAT</scene>, <scene name='pdbsite=HEM:HIS 388 Is The Axial Ligand To The Heme'>HEM</scene> and <scene name='pdbsite=SUB:ARG 120 Is Believed To Anchor The Carboxylate Of Substra ...'>SUB</scene>. Full crystallographic information is available from [http:// | 5COX is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] with <scene name='pdbligand=NAG:'>NAG</scene> and <scene name='pdbligand=HEM:'>HEM</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Prostaglandin-endoperoxide_synthase Prostaglandin-endoperoxide synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.99.1 1.14.99.1] Known structural/functional Sites: <scene name='pdbsite=ACE:SER+530+Is+Acetylated+By+Aspirin+(An+Acetyl+Group+Is+Cov+...'>ACE</scene>, <scene name='pdbsite=CAT:TYR+385+Is+Believed+To+Be+The+Amino+Acid+That+Abstracts+...'>CAT</scene>, <scene name='pdbsite=HEM:HIS+388+Is+The+Axial+Ligand+To+The+Heme'>HEM</scene> and <scene name='pdbsite=SUB:ARG+120+Is+Believed+To+Anchor+The+Carboxylate+Of+Substra+...'>SUB</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5COX OCA]. | ||
==Reference== | ==Reference== | ||
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[[Category: prostaglandin synthase]] | [[Category: prostaglandin synthase]] | ||
''Page seeded by [http:// | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Feb 3 10:53:19 2008'' | ||