4a9k: Difference between revisions

Revision as of 09:18, 11 January 2012

4a9k is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

↑ Chung CW, Dean TW, Woolven JM, Bamborough P. Fragment-based discovery of bromodomain inhibitors part 1: inhibitor binding modes and implications for lead discovery. J Med Chem. 2011 Dec 5. PMID:22136404 doi:10.1021/jm201320w

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-'''Unreleased structure'''
+[[Image:4a9k.png|left|200px]]
-The entry 4a9k is ON HOLD
+<!--
+The line below this paragraph, containing "STRUCTURE_4a9k", creates the "Structure Box" on the page.
+You may change the PDB parameter (which sets the PDB file loaded into the applet)
+or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+or leave the SCENE parameter empty for the default display.
+-->
+{{STRUCTURE_4a9k|  PDB=4a9k  |  SCENE=  }}
-Authors: Chung, C., Bamborough, P.
+===BROMODOMAIN OF HUMAN CREBBP WITH N-(4-hydroxyphenyl)acetamide===
-Description: BROMODOMAIN OF HUMAN CREBBP WITH N-(4-hydroxyphenyl)acetamide
+<!--
+The line below this paragraph, {{ABSTRACT_PUBMED_22136404}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 22136404 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_22136404}}
+==About this Structure==
+[[4a9k]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A9K OCA].
+==Reference==
+<ref group="xtra">PMID:022136404</ref><references group="xtra"/>
+[[Category: Histone acetyltransferase]]
+[[Category: Homo sapiens]]
+[[Category: Bamborough, P.]]
+[[Category: Chung, C W.]]
+[[Category: Epigenetic reader]]
+[[Category: Histone]]
+[[Category: Inhibitor]]
+[[Category: Signaling protein]]