4a9i: Difference between revisions

Revision as of 09:16, 11 January 2012

4a9i is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

↑ Chung CW, Dean TW, Woolven JM, Bamborough P. Fragment-based discovery of bromodomain inhibitors part 1: inhibitor binding modes and implications for lead discovery. J Med Chem. 2011 Dec 5. PMID:22136404 doi:10.1021/jm201320w

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+[[Image:4a9i.png|left|200px]]
-The entry 4a9i is ON HOLD
+<!--
+The line below this paragraph, containing "STRUCTURE_4a9i", creates the "Structure Box" on the page.
+You may change the PDB parameter (which sets the PDB file loaded into the applet)
+or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+or leave the SCENE parameter empty for the default display.
+-->
+{{STRUCTURE_4a9i|  PDB=4a9i  |  SCENE=  }}
-Authors: Chung, C., Bamborough, P.
+===N-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH 3-methyl-1,2,3,4- tetrahydroquinazolin-2-one===
-Description: N-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH 3-methyl-1,2,3,4-tetrahydroquinazolin-2-one
+<!--
+The line below this paragraph, {{ABSTRACT_PUBMED_22136404}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 22136404 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_22136404}}
+==About this Structure==
+[[4a9i]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A9I OCA].
+==Reference==
+<ref group="xtra">PMID:022136404</ref><references group="xtra"/>
+[[Category: Homo sapiens]]
+[[Category: Bamborough, P.]]
+[[Category: Chung, C W.]]
+[[Category: Epigenetic reader]]
+[[Category: Histone]]
+[[Category: Inhibitor]]
+[[Category: Signaling protein]]