4a4l: Difference between revisions
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===CRYSTAL STRUCTURE OF POLO-LIKE KINASE 1 IN COMPLEX WITH A 5-(2-AMINO- PYRIMIDIN-4-YL)-1H-PYRROLE INHIBITOR=== | |||
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{{ABSTRACT_PUBMED_22154349}} | |||
==About this Structure== | |||
[[4a4l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A4L OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:022154349</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Polo kinase]] | |||
[[Category: Bertrand, J A.]] | |||
[[Category: Bossi, R T.]] | |||
[[Category: Transferase]] | |||
Revision as of 09:16, 11 January 2012
CRYSTAL STRUCTURE OF POLO-LIKE KINASE 1 IN COMPLEX WITH A 5-(2-AMINO- PYRIMIDIN-4-YL)-1H-PYRROLE INHIBITORCRYSTAL STRUCTURE OF POLO-LIKE KINASE 1 IN COMPLEX WITH A 5-(2-AMINO- PYRIMIDIN-4-YL)-1H-PYRROLE INHIBITOR
Template:ABSTRACT PUBMED 22154349
About this StructureAbout this Structure
4a4l is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Caruso M, Valsasina B, Ballinari D, Bertrand J, Brasca MG, Caldarelli M, Cappella P, Fiorentini F, Gianellini LM, Scolaro A, Beria I. 5-(2-Amino-pyrimidin-4-yl)-1H-pyrrole and 2-(2-amino-pyrimidin-4-yl)-1,5,6,7-tetrahydro-pyrrolo[3,2-c]pyridin-4-one derivatives as new classes of selective and orally available Polo-like kinase 1 inhibitors. Bioorg Med Chem Lett. 2012 Jan 1;22(1):96-101. Epub 2011 Nov 23. PMID:22154349 doi:10.1016/j.bmcl.2011.11.065