2c0h: Difference between revisions
New page: left|200px<br /> <applet load="2c0h" size="450" color="white" frame="true" align="right" spinBox="true" caption="2c0h, resolution 1.60Å" /> '''X-RAY STRUCTURE OF ... |
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==About this Structure== | ==About this Structure== | ||
2C0H is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Mytilus_edulis Mytilus edulis]] with SO4 as [[http://en.wikipedia.org/wiki/ligand ligand]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.78 3.2.1.78]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2C0H OCA]]. | 2C0H is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Mytilus_edulis Mytilus edulis]] with SO4 as [[http://en.wikipedia.org/wiki/ligand ligand]]. Active as [[http://en.wikipedia.org/wiki/Mannan_endo-1,4-beta-mannosidase Mannan endo-1,4-beta-mannosidase]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.78 3.2.1.78]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2C0H OCA]]. | ||
==Reference== | ==Reference== | ||
Three-dimensional crystal structure and enzymic characterization of beta-mannanase Man5A from blue mussel Mytilus edulis., Larsson AM, Anderson L, Xu B, Munoz IG, Uson I, Janson JC, Stalbrand H, Stahlberg J, J Mol Biol. 2006 Apr 14;357(5):1500-10. Epub 2006 Jan 31. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16487541 16487541] | Three-dimensional crystal structure and enzymic characterization of beta-mannanase Man5A from blue mussel Mytilus edulis., Larsson AM, Anderson L, Xu B, Munoz IG, Uson I, Janson JC, Stalbrand H, Stahlberg J, J Mol Biol. 2006 Apr 14;357(5):1500-10. Epub 2006 Jan 31. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16487541 16487541] | ||
[[Category: Mannan endo-1,4-beta-mannosidase]] | |||
[[Category: Mytilus edulis]] | [[Category: Mytilus edulis]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: tim alpha/beta barrel]] | [[Category: tim alpha/beta barrel]] | ||
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 12:50:08 2007'' | ||
Revision as of 13:45, 30 October 2007
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X-RAY STRUCTURE OF BETA-MANNANASE FROM BLUE MUSSEL MYTILUS EDULIS
OverviewOverview
Endo-beta-1,4-d-mannanase is the key depolymerizing enzyme for, beta-1,4-mannan polymers present in the cell walls of plants and some, algae, as well as in some types of plant seeds. Endo-1,4-beta-mannanase, from blue mussel Mytilus edulis (MeMan5A) belongs to the glycoside, hydrolase (GH) family 5 enzymes. The MeMan5A structure has been determined, to 1.6A resolution using the multiple-wavelength anomalous dispersion, method at the selenium K edge with selenomethionyl MeMan5A expressed in, the yeast Pichia pastoris. As expected for GH 5 enzymes, the structure, showed a (betaalpha)(8)-barrel fold. An unusually large number of, histidine side-chains are exposed on the surface, which may relate to its, location within the crystalline style of the digestive tract of the, mussel. Kinetic ... [(full description)]
About this StructureAbout this Structure
2C0H is a [Single protein] structure of sequence from [Mytilus edulis] with SO4 as [ligand]. Active as [Mannan endo-1,4-beta-mannosidase], with EC number [3.2.1.78]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].
ReferenceReference
Three-dimensional crystal structure and enzymic characterization of beta-mannanase Man5A from blue mussel Mytilus edulis., Larsson AM, Anderson L, Xu B, Munoz IG, Uson I, Janson JC, Stalbrand H, Stahlberg J, J Mol Biol. 2006 Apr 14;357(5):1500-10. Epub 2006 Jan 31. PMID:16487541
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