3sd5: Difference between revisions

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'''Unreleased structure'''
[[Image:3sd5.jpg|left|200px]]


The entry 3sd5 is ON HOLD until Paper Publication
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{{STRUCTURE_3sd5|  PDB=3sd5  |  SCENE=  }}


Authors: Knapp, M.S., Elling, R.A.
===Crystal Structure of PI3K gamma with 5-(2,4-dimorpholinopyrimidin-6-yl)-4-(trifluoromethyl)pyridin-2-amine===


Description: Crystal Structure of PI3K gamma with 5-(2,4-dimorpholinopyrimidin-6-yl)-4-(trifluoromethyl)pyridin-2-amine
 
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{{ABSTRACT_PUBMED_22188813}}
 
==About this Structure==
[[3sd5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SD5 OCA].
 
==Reference==
<ref group="xtra">PMID:022188813</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Phosphatidylinositol-4,5-bisphosphate 3-kinase]]
[[Category: Elling, R A.]]
[[Category: Knapp, M S.]]
[[Category: Lipid kinase]]
[[Category: Transferase-transferase inhibitor complex]]

Revision as of 09:04, 4 January 2012

File:3sd5.jpg

Template:STRUCTURE 3sd5

Crystal Structure of PI3K gamma with 5-(2,4-dimorpholinopyrimidin-6-yl)-4-(trifluoromethyl)pyridin-2-amineCrystal Structure of PI3K gamma with 5-(2,4-dimorpholinopyrimidin-6-yl)-4-(trifluoromethyl)pyridin-2-amine

Template:ABSTRACT PUBMED 22188813

About this StructureAbout this Structure

3sd5 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Maira SM, Pecchi S, Huang A, Burger M, Knapp M, Sterker D, Schnell C, Guthy D, Nagel T, Wiesmann M, Brachmann SM, Fritsch C, Dorsch M, Chene P, Shoemaker K, De Pover A, Menezes D, Martiny-Baron G, Fabbro D, Wilson C, Schlegel R, Hofmann F, Garcia-Echeverria C, Sellers WR, Voliva CF. Identification and characterization of NVP-BKM120, an orally available pan class I PI3-Kinase inhibitor. Mol Cancer Ther. 2011 Dec 21. PMID:22188813 doi:10.1158/1535-7163.MCT-11-0474

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