Sandbox 208: Difference between revisions
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==Overall structure== | ==Overall structure== | ||
GDI is a 55-kDa protein containing 451 residues. The structure of GDI contains 27 β strands and 21 α helices and can be divided into two domains separated by a cleft. Firstly, a large domain I is located at the apex. Secondly, a smaller entirely α helices domain named domain II is inserted at the base of GDI. The β sheets build a relatively rigid protein carcass. The α helical regions are involved in the structural rearrangement upon Rab binding. | |||
== Substrate binding == | == Substrate binding == | ||