4a92: Difference between revisions
Jump to navigation
Jump to search
m Protected "4a92" [edit=sysop:move=sysop] |
No edit summary |
||
| Line 1: | Line 1: | ||
[[Image:4a92.jpg|left|200px]] | |||
The | <!-- | ||
The line below this paragraph, containing "STRUCTURE_4a92", creates the "Structure Box" on the page. | |||
You may change the PDB parameter (which sets the PDB file loaded into the applet) | |||
or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | |||
or leave the SCENE parameter empty for the default display. | |||
--> | |||
{{STRUCTURE_4a92| PDB=4a92 | SCENE= }} | |||
===Full-length HCV NS3-4A protease-helicase in complex with a macrocyclic protease inhibitor.=== | |||
<!-- | |||
The line below this paragraph, {{ABSTRACT_PUBMED_22160684}}, adds the Publication Abstract to the page | |||
(as it appears on PubMed at http://www.pubmed.gov), where 22160684 is the PubMed ID number. | |||
--> | |||
{{ABSTRACT_PUBMED_22160684}} | |||
==About this Structure== | |||
[[4a92]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A92 OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:022160684</ref><references group="xtra"/> | |||
[[Category: Hepatitis c virus]] | |||
[[Category: Arcy, A D.]] | |||
[[Category: Bodendorf, U.]] | |||
[[Category: Eder, J.]] | |||
[[Category: Raman, P.]] | |||
[[Category: Schiering, N.]] | |||
[[Category: Simic, O.]] | |||
[[Category: Svergun, D I.]] | |||
[[Category: Drug design]] | |||
[[Category: Hydrolase]] | |||
Revision as of 10:26, 28 December 2011
Full-length HCV NS3-4A protease-helicase in complex with a macrocyclic protease inhibitor.Full-length HCV NS3-4A protease-helicase in complex with a macrocyclic protease inhibitor.
Template:ABSTRACT PUBMED 22160684
About this StructureAbout this Structure
4a92 is a 2 chain structure with sequence from Hepatitis c virus. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Schiering N, D'Arcy A, Villard F, Simic O, Kamke M, Monnet G, Hassiepen U, Svergun DI, Pulfer R, Eder J, Raman P, Bodendorf U. A macrocyclic HCV NS3/4A protease inhibitor interacts with protease and helicase residues in the complex with its full-length target. Proc Natl Acad Sci U S A. 2011 Dec 12. PMID:22160684 doi:10.1073/pnas.1110534108