Sandbox 215: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
=== Cholesteryl Ester Transfer Protein (CETP) === | === Cholesteryl Ester Transfer Protein (CETP) === | ||
[[Image: | [[Image:2obd.png|left|200px]] | ||
{{ | {{STRUCTURE_2obd| PDB=2obd | SCENE= }} | ||
==Introduction== | ==Introduction== | ||
Revision as of 16:36, 24 December 2011
Cholesteryl Ester Transfer Protein (CETP)Cholesteryl Ester Transfer Protein (CETP)
| |||||||||
| 2obd, resolution 2.10Å () | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Ligands: | , , , , , , , | ||||||||
| Gene: | CETP (Homo sapiens) | ||||||||
| |||||||||
| |||||||||
| |||||||||
| Resources: | FirstGlance, OCA, RCSB, PDBsum | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
IntroductionIntroduction
Cholesteryl Ester Transfer Protein is a plasma glycoprotein which is implicated in the transport of cholesteryl esters from the atheroprotective high-density lipoproteins (HDL) to the atherogenic lower-density lipoproteins (LDL). The cristal structure of CETP at 2,2-Å resolution in complex with four bound lipid molecules shows a long tunnel which traverses the core of the molecule and has two distinct large openings allowing lipid access. This tunnel is plugged by an amphiphilic phosphatidylcholine at each end.
|