RuBisCO

spinqualitylabelsall models PDB ID 1rcx Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image
Spinach RuBisCO complex with substrate ribulose-1,5- bisphosphate, 1rcx
Ligands:
Activity:	Ribulose-bisphosphate carboxylase, with EC number 4.1.1.39
Structural annotation: Resources: CATH : 1Rcxb02, 1Rcxb01, 1Rcxc00, 1Rcxe01, 1Rcxe02, 1Rcxf00, 1Rcxh02, 1Rcxh01, 1Rcxi00, 1Rcxk02, 1Rcxk01, 1Rcxl01, 1Rcxl02, 1Rcxm00, 1Rcxo02, 1Rcxo01, 1Rcxp00, 1Rcxr02, 1Rcxr01, 1Rcxs00, 1Rcxt00, 1Rcxv01, 1Rcxv02, 1Rcxw00 InterPro : Ipr000685, Ipr000894 Pfam : PF00016, PF02788, PF00101 SCOP : d1rcxb2, d1rcxb1, d1rcxc_, d1rcxe2, d1rcxe1, d1rcxf_, d1rcxh2, d1rcxh1, d1rcxi_, d1rcxk2, d1rcxk1, d1rcxl2, d1rcxl1, d1rcxm_, d1rcxo2, d1rcxo1, d1rcxp_, d1rcxr1, d1rcxr2, d1rcxs_, d1rcxt_, d1rcxv2, d1rcxv1, d1rcxw_ UniProt : P00875, P00870
Functional annotation: Cellular component: chloroplast chloroplast ribulose bisphosphate carboxylase complex Biological process: carbon utilization by fixation of carbon dioxide photosynthesis photorespiration reductive pentose-phosphate cycle Molecular function: lyase activity magnesium ion binding metal ion binding ribulose-bisphosphate carboxylase activity monooxygenase activity oxidoreductase activity
Evolutionary conservation: Toggle Conservation Colors: Rows = identical sequences: Further Information: Caveats, Explanation, Complete Results at ConSurfDB
Resources:	FirstGlance, OCA, PDBsum, RCSB
Coordinates:	save as pdb, mmCIF, xml

Ribulose-1,5-bisphosphate carboxylase oxygenase – RuBisCO (RBCD) catalyzes the first step in carbon fixation. RBCD carboxylates or oxygenates ribulose-1,5-bisphosphate with CO2 or O2. RBCD usually consists of a large chain (LSMT – large subunit methyltrasferase) and small chain. 2-carboxylarabinitol-1,5-bisphosphate (2-CABP) is an inhibitor of RCBD. Some additional details in Ribulose-1,5-bisphosphate carboxylase/oxygenase.

3D Structures of RuBisCO3D Structures of RuBisCO

RuBisCORuBisCO

3rg6 – RBCO – Synechococcus elongatus
3qfw - RBCO large subunit – Rhodopseudomonas palustris
1uzh, 1gk8 – CrRBCO – Chlamydomonas reinhardtii
1uw9, 1uwa – CrRBCO (mutant)
1svd – RBCD – Halothiobacillus neapolitanus
1bxn – RBCO – Cupriavidus necator
1aus - spRBCO – spinach
1rba - RrRBCO (mutant) – Rhododpirillum rubrum
5rub - RrRBCO
2wvw – RBCO – Anabena – Cryo EM
2vdh, 2vdi, 2v67, 2v68, 2v63, 2v69, 2v6a - CrRBCO (mutant)
1mlv - pRBCO LSMT – pea
2cxe, 2cwx – PhRBCO - Pyrococcus horikoshii
1uzd – CrRBCO/spRBCO

RuBisCO complex with inhibitor 2-CABPRuBisCO complex with inhibitor 2-CABP

3kdn, 3a12 – TkRBCO III + 2-CABP – Thermococcus kodakaraensis
3kdo, 3a13 - TkRBCO III (mutant) + 2-CABP
1ir2 - CrRBCO + 2-CABP
1upm, 1upp, 1rbo, 3ruc - spRBCO + 2-CABP + Ca
1ir1 - spRBCO + 2-CABP + CO2 + Mg
1wdd – RBCO + 2-CABP – rice
1bwv - RBCO + 2-CABP – Galdieria partita

RuBisCO complex with productRuBisCO complex with product

1aa1 – spRBCO + phosphoglycerate
1rus - RrRBCO + phosphoglycerate

RuBisCO complex with substrateRuBisCO complex with substrate

1rcx, 1rxo – spRBCO + ribulose-1,5-bisphosphate

RuBisCO complexesRuBisCO complexes

2h21 – pRBCO LSMT + AdoMet
2h23 - pRBCO LSMT + AdoHcy
2h2e, 1ozv, 1p0y - pRBCO LSMT + AdoMet + lysine
2h2j - pRBCO LSMT + sinefungin
2d69 – PhRBCO + sulfate
1rco - spRBCO + xylulose-diol-1,5-bisphosphate
2rus - RrRBCO + CO2 + Mg
1ej7 – RBCO + phosphate - tobacco