3sl4: Difference between revisions
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===Crystal structure of the catalytic domain of PDE4D2 with compound 10D=== | ===Crystal structure of the catalytic domain of PDE4D2 with compound 10D=== | ||
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==About this Structure== | ==About this Structure== | ||
[[3sl4]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SL4 OCA]. | [[3sl4]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SL4 OCA]. | ||
==Reference== | |||
<ref group="xtra">PMID:022030030</ref><references group="xtra"/> | |||
[[Category: 3',5'-cyclic-nucleotide phosphodiesterase]] | [[Category: 3',5'-cyclic-nucleotide phosphodiesterase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
Revision as of 13:42, 14 December 2011
Crystal structure of the catalytic domain of PDE4D2 with compound 10DCrystal structure of the catalytic domain of PDE4D2 with compound 10D
Template:ABSTRACT PUBMED 22030030
About this StructureAbout this Structure
3sl4 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Nankervis JL, Feil SC, Hancock NC, Zheng Z, Ng HL, Morton CJ, Holien JK, Ho PW, Frazzetto MM, Jennings IG, Manallack DT, Martin TJ, Thompson PE, Parker MW. Thiophene inhibitors of PDE4: Crystal structures show a second binding mode at the catalytic domain of PDE4D2. Bioorg Med Chem Lett. 2011 Dec 1;21(23):7089-93. Epub 2011 Oct 5. PMID:22030030 doi:10.1016/j.bmcl.2011.09.109