Porin: Difference between revisions

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[[Image:Ompc.png|left|250px|thumb|Crystal structure of Porin OmpC from ''E. coli'', [[2j1n]]]]
[[Image:Ompc.png|left|250px|thumb|Crystal structure of Porin OmpC from ''E. coli'', [[2j1n]]]]
{{STRUCTURE_2j1n|  PDB=2j1n  | SIZE=300| SCENE=Porin/Cv/1 |right|CAPTION=Porin OmpC from ''E. coli'', [[2j1n]] }}
{{STRUCTURE_2j1n|  PDB=2j1n  | SIZE=400| SCENE=Porin/Cv/1 |right|CAPTION=Porin OmpC from ''E. coli'', [[2j1n]] }}
[[Porin]] or '''Outer Membrane Proteins''' '''(Omps)''' act as channels which allow passive diffusion of sugars, ions and amino acids.  They are beta barrel proteins which traverse the cell membrane.  In ''E. coli'' they are named according to their genes: C, F, G (OmpC, OmpF, Ompg). See some details in [[OmpF]].  '''Voltage-Dependent Anion Channel (VDAC)''' is ion channel Omp found in outer mitochondrial membrane.  In Pseudomonas aeruginosa the porin gene products are named OprD, OprK, OprP. The images at the left and at the right correspond to one representative porin structure, ''i.e.'' crystal structure osmoporin OmpC from ''Escherichia coli'' ([[2j1n]]). OmpC has three beta-barrels associated to form a <scene name='Porin/Cv/2'>tight trimer</scene> <ref>PMID:16949612</ref>.
[[Porin]] or '''Outer Membrane Proteins''' '''(Omps)''' act as channels which allow passive diffusion of sugars, ions and amino acids.  They are beta barrel proteins which traverse the cell membrane.  In ''E. coli'' they are named according to their genes: C, F, G (OmpC, OmpF, Ompg). See some details in [[OmpF]].  '''Voltage-Dependent Anion Channel (VDAC)''' is ion channel Omp found in outer mitochondrial membrane.  In Pseudomonas aeruginosa the porin gene products are named OprD, OprK, OprP. The images at the left and at the right correspond to one representative porin structure, ''i.e.'' crystal structure osmoporin OmpC from ''Escherichia coli'' ([[2j1n]]). OmpC has three beta-barrels associated to form a <scene name='Porin/Cv/2'>tight trimer</scene> <ref>PMID:16949612</ref>.


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== Porin ==
== Porin ==


''Updated December 2011''


[[2xe5]], [[2xe1]], [[2xe2]], [[2xe3]], [[2j1n]] – EcOmpC – ''Escherichia coli''<br />
[[2xe5]], [[2xe1]], [[2xe2]], [[2xe3]], [[2j1n]] – EcOmpC – ''Escherichia coli''<br />
[[3k19]], [[3k1b]], [[2zfg]], [[1omf]], [[2omf]], [[1opf]] – EcOmpF<br />
[[3k19]], [[3k1b]], [[2zfg]], [[1omf]], [[2omf]], [[1opf]] – EcOmpF<br />
[[3nb3]] – EcOmpA + EcOmpC - EM<br />
[[1hxt]], [[1hxu]], [[1hxx]], [[1bt9]], [[1gfm]], [[1gfn]], [[1gfo]], [[1gfp]], [[1gfq]], [[1mpf]] – EcOmpF (mutant)<br />
[[1hxt]], [[1hxu]], [[1hxx]], [[1bt9]], [[1gfm]], [[1gfn]], [[1gfo]], [[1gfp]], [[1gfq]], [[1mpf]] – EcOmpF (mutant)<br />
[[2iwv]], [[2iww]], [[2f1c]] - EcOmpG<br />
[[2iwv]], [[2iww]], [[2f1c]] - EcOmpG<br />
[[2x9k]] - EcOmpG (mutant)<br />
[[2wjq]], [[2wjr]] – EcOmp NANC<br />
[[2wjq]], [[2wjr]] – EcOmp NANC<br />
[[1pho]] - EcOmp<br />
[[1pho]] - EcOmp<br />
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[[2fgr]] - DaOmp32 - ''Delftia acidovorans''<br />
[[2fgr]] - DaOmp32 - ''Delftia acidovorans''<br />
[[1a0s]], [[1mpr]] - StOmp - ''Salmonella typhimurium''<br />
[[1a0s]], [[1mpr]] - StOmp - ''Salmonella typhimurium''<br />
[[3nsg]] - StOmpF<br />
[[2prn]], [[1bh3]], [[3prn]], [[5prn]], [[6prn]], [[7prn]], [[8prn]] – RbOmp (mutant) - ''Rhodopseudomonas blastica''<br />
[[2prn]], [[1bh3]], [[3prn]], [[5prn]], [[6prn]], [[7prn]], [[8prn]] – RbOmp (mutant) - ''Rhodopseudomonas blastica''<br />
[[1prn]] - RbOmp<br />
[[1prn]] - RbOmp<br />

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Michal Harel, Jaime Prilusky, Joel L. Sussman, Karsten Theis