3thb: Difference between revisions
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{{STRUCTURE_3thb| PDB=3thb | SCENE= }} | |||
===Structure of PLK1 kinase domain in complex with a benzolactam-derived inhibitor=== | |||
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{{ABSTRACT_PUBMED_22070629}} | |||
==About this Structure== | |||
[[3thb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3THB OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:022070629</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Polo kinase]] | |||
[[Category: Sintchak, M D.]] | |||
[[Category: Kinase domain]] | |||
[[Category: Transferase-transferase inhibitor complex]] | |||
Revision as of 22:03, 23 November 2011
Structure of PLK1 kinase domain in complex with a benzolactam-derived inhibitorStructure of PLK1 kinase domain in complex with a benzolactam-derived inhibitor
Template:ABSTRACT PUBMED 22070629
About this StructureAbout this Structure
3thb is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Duffey MO, Vos TJ, Adams R, Alley J, Anthony J, Barrett C, Bharathan I, Bowman D, Bump NJ, Chau R, Cullis C, Driscoll DL, Elder A, Forsyth N, Frazer J, Guo J, Guo L, Hyer ML, Janowick D, Kulkarni B, Lai SJ, Lasky K, Li G, Li J, Liao D, Little J, Peng B, Qian MG, Reynolds DJ, Rezaei M, Scott MP, Sells TB, Shinde V, Shi QJ, Sintchak MD, Soucy F, Sprott KT, Stroud SG, Nestor M, Visieres I, Weatherhead G, Ye Y, D'Amore N. Discovery of a Potent and Orally Bioavailable Benzolactam-Derived Inhibitor of Polo-Like Kinase 1 (MLN0905). J Med Chem. 2011 Nov 9. PMID:22070629 doi:10.1021/jm2011172