3pr0: Difference between revisions
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===Crystal Structure of a Covalently Bound alpha-Ketoheterocycle Inhibitor (Phenhexyl/Oxadiazole/Pyridine) to a Humanized Variant of Fatty Acid Amide Hydrolase=== | |||
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{{ABSTRACT_PUBMED_21355555}} | |||
==About this Structure== | |||
[[3pr0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PR0 OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:021355555</ref><references group="xtra"/> | |||
[[Category: Amidase]] | |||
[[Category: Rattus norvegicus]] | |||
[[Category: Boger, D L.]] | |||
[[Category: Han, G W.]] | |||
[[Category: Mileni, M.]] | |||
[[Category: Stevens, R C.]] | |||
[[Category: Alpha-ketoheterocycle]] | |||
[[Category: Endocannabinoid degradation]] | |||
[[Category: Faah]] | |||
[[Category: Hydrolase-hydrolase inhibitor complex]] | |||
[[Category: Membrane protein]] | |||
[[Category: Oxadiazole]] | |||
[[Category: Protein-inhibitor complex]] | |||
Revision as of 15:15, 16 November 2011
Crystal Structure of a Covalently Bound alpha-Ketoheterocycle Inhibitor (Phenhexyl/Oxadiazole/Pyridine) to a Humanized Variant of Fatty Acid Amide HydrolaseCrystal Structure of a Covalently Bound alpha-Ketoheterocycle Inhibitor (Phenhexyl/Oxadiazole/Pyridine) to a Humanized Variant of Fatty Acid Amide Hydrolase
Template:ABSTRACT PUBMED 21355555
About this StructureAbout this Structure
3pr0 is a 2 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Mileni M, Garfunkle J, Ezzili C, Cravatt BF, Stevens RC, Boger DL. Fluoride-mediated capture of a noncovalent bound state of a reversible covalent enzyme inhibitor: X-ray crystallographic analysis of an exceptionally potent alpha-ketoheterocycle inhibitor of fatty acid amide hydrolase. J Am Chem Soc. 2011 Mar 23;133(11):4092-100. Epub 2011 Feb 28. PMID:21355555 doi:10.1021/ja110877y