3vhe: Difference between revisions

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'''Unreleased structure'''
[[Image:3vhe.jpg|left|200px]]


The entry 3vhe is ON HOLD
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{{STRUCTURE_3vhe|  PDB=3vhe |  SCENE=  }}


Authors: Oguro, Y., Miyamoto, N., Okada, K., Takagi, T., Iwata, H., Awazu, Y., Miki, H., Hori, A., Kamiyama, K., Imanura, S.
===Crystal structure of human VEGFR2 kinase domain with a novel pyrrolopyrimidine inhibitor.===


Description: Crystal structure of human VEGFR2 kinase domain with a novel pyrrolopyrimidine inhibitor.
 
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{{ABSTRACT_PUBMED_20833055}}
 
==About this Structure==
[[3vhe]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VHE OCA].
 
==Reference==
<ref group="xtra">PMID:020833055</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Awazu, Y.]]
[[Category: Hori, A.]]
[[Category: Imanura, S.]]
[[Category: Iwata, H.]]
[[Category: Kamiyama, K.]]
[[Category: Miki, H.]]
[[Category: Miyamoto, N.]]
[[Category: Oguro, Y.]]
[[Category: Okada, K.]]
[[Category: Takagi, T.]]
[[Category: Kinase]]
[[Category: Kinase domain]]
[[Category: Transferase-transferase inhibitor complex]]

Revision as of 11:22, 2 November 2011

File:3vhe.jpg

Template:STRUCTURE 3vhe

Crystal structure of human VEGFR2 kinase domain with a novel pyrrolopyrimidine inhibitor.Crystal structure of human VEGFR2 kinase domain with a novel pyrrolopyrimidine inhibitor.

Template:ABSTRACT PUBMED 20833055

About this StructureAbout this Structure

3vhe is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Oguro Y, Miyamoto N, Okada K, Takagi T, Iwata H, Awazu Y, Miki H, Hori A, Kamiyama K, Imamura S. Design, synthesis, and evaluation of 5-methyl-4-phenoxy-5H-pyrrolo[3,2-d]pyrimidine derivatives: novel VEGFR2 kinase inhibitors binding to inactive kinase conformation. Bioorg Med Chem. 2010 Oct 15;18(20):7260-73. Epub 2010 Aug 13. PMID:20833055 doi:10.1016/j.bmc.2010.08.017

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