3tu7: Difference between revisions
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===Human alpha-thrombin complexed with N-(methylsulfonyl)-D-phenylalanyl-N-((1-carbamimidoyl-4-piperidinyl)methyl)-l-prolinamide (BMS-189664)=== | |||
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{{ABSTRACT_PUBMED_11738570}} | |||
==About this Structure== | |||
[[3tu7]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Hirudo_medicinalis Hirudo medicinalis] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TU7 OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:011738570</ref><references group="xtra"/> | |||
[[Category: Hirudo medicinalis]] | |||
[[Category: Homo sapiens]] | |||
[[Category: Thrombin]] | |||
[[Category: Malley, M.]] | |||
[[Category: Sack, J S.]] | |||
[[Category: Hydrolase-hydrolase inhibitor complex]] | |||
[[Category: Serine protease]] | |||
Revision as of 10:49, 30 October 2011
Human alpha-thrombin complexed with N-(methylsulfonyl)-D-phenylalanyl-N-((1-carbamimidoyl-4-piperidinyl)methyl)-l-prolinamide (BMS-189664)Human alpha-thrombin complexed with N-(methylsulfonyl)-D-phenylalanyl-N-((1-carbamimidoyl-4-piperidinyl)methyl)-l-prolinamide (BMS-189664)
Template:ABSTRACT PUBMED 11738570
About this StructureAbout this Structure
3tu7 is a 3 chain structure with sequence from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Das J, Kimball SD, Hall SE, Han WC, Iwanowicz E, Lin J, Moquin RV, Reid JA, Sack JS, Malley MF, Chang CY, Chong S, Wang-Iverson DB, Roberts DG, Seiler SM, Schumacher WA, Ogletree ML. Molecular design and structure--activity relationships leading to the potent, selective, and orally active thrombin active site inhibitor BMS-189664. Bioorg Med Chem Lett. 2002 Jan 7;12(1):45-9. PMID:11738570