2wp5: Difference between revisions

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[[Image:2wp5.png|left|200px]]
[[Image:2wp5.jpg|left|200px]]


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===TRYPANOSOMA BRUCEI TRYPANOTHIONE REDUCTASE IN COMPLEX WITH 3,4-DIHYDROQUINAZOLINE INHIBITOR (DDD00065414)===
===TRYPANOSOMA BRUCEI TRYPANOTHIONE REDUCTASE IN COMPLEX WITH 3,4-DIHYDROQUINAZOLINE INHIBITOR (DDD00065414)===


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{{ABSTRACT_PUBMED_21851087}}


==About this Structure==
==About this Structure==
2WP5 is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WP5 OCA].  
[[2wp5]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WP5 OCA].  
 
==Reference==
<ref group="xtra">PMID:021851087</ref><references group="xtra"/>
[[Category: Trypanosoma brucei]]
[[Category: Trypanosoma brucei]]
[[Category: Trypanothione-disulfide reductase]]
[[Category: Trypanothione-disulfide reductase]]
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[[Category: Sleeping sickness]]
[[Category: Sleeping sickness]]
[[Category: Trypanosomiasis]]
[[Category: Trypanosomiasis]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 13 10:44:47 2010''

Revision as of 10:28, 30 October 2011

File:2wp5.png

Template:STRUCTURE 2wp5

TRYPANOSOMA BRUCEI TRYPANOTHIONE REDUCTASE IN COMPLEX WITH 3,4-DIHYDROQUINAZOLINE INHIBITOR (DDD00065414)TRYPANOSOMA BRUCEI TRYPANOTHIONE REDUCTASE IN COMPLEX WITH 3,4-DIHYDROQUINAZOLINE INHIBITOR (DDD00065414)

Template:ABSTRACT PUBMED 21851087

About this StructureAbout this Structure

2wp5 is a 4 chain structure with sequence from Trypanosoma brucei. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Patterson S, Alphey MS, Jones DC, Shanks EJ, Street IP, Frearson JA, Wyatt PG, Gilbert IH, Fairlamb AH. Dihydroquinazolines as a Novel Class of Trypanosoma brucei Trypanothione Reductase Inhibitors: Discovery, Synthesis, and Characterization of their Binding Mode by Protein Crystallography. J Med Chem. 2011 Oct 13;54(19):6514-30. Epub 2011 Sep 1. PMID:21851087 doi:10.1021/jm200312v

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