DNA methyltransferase: Difference between revisions
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{{STRUCTURE_1qnt| PDB=1qnt | SIZE=400| SCENE= |right|CAPTION=Human O6-methylguanine DNA methyltransferase, [[1qnt]] }} | |||
'''DNA methyltransferase''' (DNMT) catalyzes the transfer of methyl group to DNA. DNMT uses S-adenosyl methionine (SAM) as the methyl donor. | '''DNA methyltransferase''' (DNMT) catalyzes the transfer of methyl group to DNA. DNMT uses S-adenosyl methionine (SAM) as the methyl donor. | ||
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== 3D Structures of DNA methyltransferase == | |||
===Methylguanine DNMT=== | ===Methylguanine DNMT=== | ||
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[[1nw7]] - RsN6-adenine DNMT + S-adenonosyl cysteine | [[1nw7]] - RsN6-adenine DNMT + S-adenonosyl cysteine | ||
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Revision as of 00:00, 30 September 2011
DNA methyltransferase (DNMT) catalyzes the transfer of methyl group to DNA. DNMT uses S-adenosyl methionine (SAM) as the methyl donor.
3D Structures of DNA methyltransferase3D Structures of DNA methyltransferase
Methylguanine DNMTMethylguanine DNMT
1sfe – O6-methylguanine DNMT C terminal – Escherichia coli
1qnt, 1eh6, 3llr - hO6-methylguanine DNMT – human
1t38 - hO6-methylguanine DNMT (mutant) + DNA
1t39, 1yfh - hO6-methylguanine DNMT + DNA
1eh7 - hO6-methylguanine DNMT methylated
1eh8 - hO6-methylguanine DNMT benzylated
1wrj - O6-methylguanine DNMT - Sulfolobus tokodaii
2g7h - O6-methylguanine DNMT – Methanocaldococcus jannaschii
2kif, 2kim - O6-methylguanine DNMT – Vibrio parahaemolyticus - NMR
Methylcytosine DNMTMethylcytosine DNMT
2qrv - h-cytosine DNMT
3epz - h-cytosine DNMT replecation foci-targeting sequence
3flg - h-cytosine DNMT ADD domain
3a1a - h-cytosine DNMT PWWP domain
3av4 - m-cytosine DNMT – mouse
2c7o, 2c7p, 2c7q, 2c7r, 3pta – Hh-cytosine DNMT + DNA + S-adenonosyl cysteine
2uyc, 2uyh, 2uz4 - Hh-cytosine DNMT (mutant) + DNA + S-adenonosyl cysteine
3a1b - h-cytosine DNMT ADD domain + histone H3
3pt6, 3pt9 – m-cytosine DNMT + DNA
3av5 - m-cytosine DNMT + S-adenonosyl cysteine
3av6 - m-cytosine DNMT + SAM
3swr - h-cytosine DNMT + sinefungin
1fjx – HhDNMT (mutant) + DNA + S-adenonosyl cysteine - Haemophilus haemolyticus
Methyladenine DNMTMethyladenine DNMT
1nw5 – RsN6-adenine DNMT + SAM – Rhodobacter sphaeroides
1nw6 - RsN6-adenine DNMT + sinefungin
1nw7 - RsN6-adenine DNMT + S-adenonosyl cysteine