3qu8: Difference between revisions

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'''Unreleased structure'''
[[Image:3qu8.jpg|left|200px]]


The entry 3qu8 is ON HOLD until Paper Publication
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{{STRUCTURE_3qu8|  PDB=3qu8  |  SCENE=  }}


Authors: Shah, M.B., Pascual, J., Stout, C.D., Halpert, J.R.
===Crystal structure of a human cytochrome P450 2B6 (Y226H/K262R) in complex with the inhibitor 4-(4-Nitrobenzyl)pyridine.===


Description: Crystal structure of a human cytochrome P450 2B6 (Y226H/K262R) in complex with the inhibitor 4-(4-Nitrobenzyl)pyridine.
 
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{{ABSTRACT_PUBMED_21875942}}
 
==About this Structure==
[[3qu8]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QU8 OCA].
 
==Reference==
<ref group="xtra">PMID:021875942</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Unspecific monooxygenase]]
[[Category: Halpert, J R.]]
[[Category: Pascual, J.]]
[[Category: Shah, M B.]]
[[Category: Stout, C D.]]
[[Category: Cyp2b6]]
[[Category: Cytochrome p450 2b6]]
[[Category: Endoplasmic reticulum]]
[[Category: Heme]]
[[Category: Iron]]
[[Category: Membrane]]
[[Category: Membrane protein]]
[[Category: Metal binding]]
[[Category: Microsome]]
[[Category: Monooxygenase]]
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
[[Category: P450]]
[[Category: Phosphoprotein]]

Revision as of 09:01, 21 September 2011

File:3qu8.jpg

Template:STRUCTURE 3qu8

Crystal structure of a human cytochrome P450 2B6 (Y226H/K262R) in complex with the inhibitor 4-(4-Nitrobenzyl)pyridine.Crystal structure of a human cytochrome P450 2B6 (Y226H/K262R) in complex with the inhibitor 4-(4-Nitrobenzyl)pyridine.

Template:ABSTRACT PUBMED 21875942

About this StructureAbout this Structure

3qu8 is a 6 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Shah MB, Pascual J, Zhang Q, Stout CD, Halpert JR. Structures of Cytochrome P450 2B6 Bound to 4-Benzylpyridine and 4-(4-Nitrobenzyl)pyridine: Insight into Inhibitor Binding and Rearrangement of Active Site Side Chains. Mol Pharmacol. 2011 Aug 29. PMID:21875942 doi:10.1124/mol.111.074427

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