Aconitase: Difference between revisions

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Thus, the overall reaction that aconitase catalyzes is: Citrate ←→cis-Aconitate←→Isocitrate, as seen below:
Thus, the overall reaction that aconitase catalyzes is: Citrate ←→cis-Aconitate←→Isocitrate, as seen below:
[[ Image:Aconitase.JPG]]
[[ Image:Aconitase.JPG]]
A more stereochemical view at the reaction shows that the aconitate intermediate has to make a 180 degree flip in order to start the other half of the reaction:
[[Image:Aconitase steps stereo.png|400px]]


==Regulation==
==Regulation==

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Ralf Stephan, Eran Hodis, Anthony Noles, Alexander Berchansky, David Canner, Jaime Prilusky, Michal Harel, Joel L. Sussman, Angel Herraez