1aw6: Difference between revisions
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[[Image:1aw6.gif|left|200px]]<br /><applet load="1aw6" size=" | [[Image:1aw6.gif|left|200px]]<br /><applet load="1aw6" size="350" color="white" frame="true" align="right" spinBox="true" | ||
caption="1aw6" /> | caption="1aw6" /> | ||
'''GAL4 (CD), NMR, 24 STRUCTURES'''<br /> | '''GAL4 (CD), NMR, 24 STRUCTURES'''<br /> | ||
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==About this Structure== | ==About this Structure== | ||
1AW6 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] with CD as [http://en.wikipedia.org/wiki/ligand ligand]. This structure superseeds the now removed PDB entry 125D. Known structural/functional Sites: <scene name='pdbsite=CD4:Cd Binding Site'>CD4</scene> and <scene name='pdbsite=CD5:Cd Binding Site'>CD5</scene>. Full crystallographic information is available from [http:// | 1AW6 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] with <scene name='pdbligand=CD:'>CD</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. This structure superseeds the now removed PDB entry 125D. Known structural/functional Sites: <scene name='pdbsite=CD4:Cd+Binding+Site'>CD4</scene> and <scene name='pdbsite=CD5:Cd+Binding+Site'>CD5</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AW6 OCA]. | ||
==Reference== | ==Reference== | ||
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[[Category: transcription regulation]] | [[Category: transcription regulation]] | ||
''Page seeded by [http:// | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Feb 3 09:31:51 2008'' | ||
Revision as of 10:31, 3 February 2008
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GAL4 (CD), NMR, 24 STRUCTURES
OverviewOverview
We have refined the solution structure of cadmium-bound GAL4 and present, its 15N and 1H NMR assignments. The root-mean-square (rms) deviation to, the average structure was 0.4 +/- 0.05 A for backbone atoms, and 0.9 +/-, 0.1 A for all heavy atoms. The three-bond heteronuclear 3J(113Cd,1H), coupling constants were found to disobey a Karplus-type relationship, which was attributable to the unusual constraints imposed by the, bimetal-thiolate cluster in GAL4. We conclude that the structural, parameters that correlate to 3J(113Cd,1H) are complex.
About this StructureAbout this Structure
1AW6 is a Single protein structure of sequence from Saccharomyces cerevisiae with as ligand. This structure superseeds the now removed PDB entry 125D. Known structural/functional Sites: and . Full crystallographic information is available from OCA.
ReferenceReference
Refined solution structure of the DNA-binding domain of GAL4 and use of 3J(113Cd,1H) in structure determination., Baleja JD, Thanabal V, Wagner G, J Biomol NMR. 1997 Dec;10(4):397-401. PMID:9460244
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