3sr5: Difference between revisions
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===S. aureus Dihydrofolate Reductase complexed with novel 7-aryl-2,4-diaminoquinazolines=== | |||
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{{ABSTRACT_PUBMED_21831637}} | |||
==About this Structure== | |||
[[3sr5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SR5 OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:021831637</ref><references group="xtra"/> | |||
[[Category: Dihydrofolate reductase]] | |||
[[Category: Staphylococcus aureus]] | |||
[[Category: Hilgers, M.]] | |||
[[Category: Dhfr]] | |||
[[Category: Dihydrofolate reductase]] | |||
[[Category: Drug design]] | |||
[[Category: Enzyme inhibitor]] | |||
[[Category: Folate]] | |||
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]] | |||
Revision as of 09:47, 31 August 2011
S. aureus Dihydrofolate Reductase complexed with novel 7-aryl-2,4-diaminoquinazolinesS. aureus Dihydrofolate Reductase complexed with novel 7-aryl-2,4-diaminoquinazolines
Template:ABSTRACT PUBMED 21831637
About this StructureAbout this Structure
3sr5 is a 1 chain structure with sequence from Staphylococcus aureus. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Li X, Hilgers M, Cunningham M, Chen Z, Trzoss M, Zhang J, Kohnen L, Lam T, Creighton C, Gc K, Nelson K, Kwan B, Stidham M, Brown-Driver V, Shaw KJ, Finn J. Structure-based design of new DHFR-based antibacterial agents: 7-aryl-2,4-diaminoquinazolines. Bioorg Med Chem Lett. 2011 Sep 15;21(18):5171-6. Epub 2011 Jul 23. PMID:21831637 doi:10.1016/j.bmcl.2011.07.059