Ouabain: Difference between revisions
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=Ouabain= | =Ouabain= | ||
<scene name='Sandbox_60/Ouabain_3d/1'>Ouabain</scene> is a cardiac glycoside that inhibits ATP-dependent sodium-potassium exchange across cell membranes. The binding of ouabain to the sodium-potassium pump (also called Na+/K+ ATPase) prevents the conformational changes necessary for its proper function. This affects intracellular ion composition in various ways with various effects, depending on the cell and the dosage. The compound has therefore been utilized in medicine, both as a drug and in research related to active membrane transport. | <scene name='Sandbox_60/Ouabain_3d/1'>Ouabain</scene> is a cardiac glycoside that inhibits ATP-dependent sodium-potassium exchange across cell membranes. The binding of ouabain to the sodium-potassium pump (also called Na+/K+ ATPase) prevents the conformational changes necessary for its proper function. This affects intracellular ion composition in various ways with various effects, depending on the cell and the dosage. The compound has therefore been utilized in medicine, both as a drug and in research related to active membrane transport. | ||
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==Target Protein: Na+/K+ ATPase== | ==Target Protein: Na+/K+ ATPase== | ||
[[Image:498px-Scheme sodium-potassium pump-en-2.svg.png|thumb|right|upright=3.0]] | [[Image:498px-Scheme sodium-potassium pump-en-2.svg.png|thumb|right|upright=3.0]] | ||