PhoP-PhoQ: Difference between revisions
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Michal Harel (talk | contribs) New page: {{STRUCTURE_3bq8| PDB=3bq8 | SIZE=400| SCENE= |right|CAPTION=''E. coli'' PhoQ, 3bq8 }} '''PhoP-PhoQ''' is a two-component system which governs virulence and mediates the adptation ... |
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{{STRUCTURE_3bq8| PDB=3bq8 | SIZE=400| SCENE= |right|CAPTION=''E. coli'' Se-Met PhoQ complex with Ni+2 and acetic acid, [[3bq8]] }} | |||
{{STRUCTURE_3bq8| PDB=3bq8 | SIZE=400| SCENE= |right|CAPTION=''E. coli'' PhoQ, [[3bq8]] }} | |||
'''PhoP-PhoQ''' is a two-component system which governs virulence and mediates the adptation to Mg+2-limiting conditions. PhoP is a response regulator and PhoQ is the inner membrane sensor. See details on PhoP in [[PhoP Regulatory Domain]]. | '''PhoP-PhoQ''' is a two-component system which governs virulence and mediates the adptation to Mg+2-limiting conditions. PhoP is a response regulator and PhoQ is the inner membrane sensor. See details on PhoP in [[PhoP Regulatory Domain]]. | ||
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== 3D Structures of PhoP-PhoQ== | == 3D Structures of PhoP-PhoQ== | ||
===PhoP=== | |||
[[3r0j]] – MtPhoP – ''Mycobacterium tuberculosis''<br /> | |||
[[2pmu]] – MtPhoP DNA-binding domain<br /> | |||
[[2pkx]] – EcPhoP regulatory domain (mutant) – ''Escherichia coli''<br /> | |||
[[2pl1]] - EcPhoP regulatory domain (mutant) + BeF3<br /> | |||
[[1mvo]] – PhoP N terminal – ''Bacillus subtilis'' | |||
===PhoQ=== | |||
[[3cgy]] – StPhoQ catalytic domain + radicicol – ''Salmonella typhimurium''<br /> | |||
[[3cgz]] - StPhoQ catalytic domain<br /> | |||
[[1yax]] - StPhoQ sensor domain (mutant)<br /> | |||
[[3bq8]] – EcPhoQ<br /> | |||
[[3bqa]] – EcPhoQ (mutant)<br /> | |||
[[1id0]] – EcPhoQ kinase domain | |||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 11:55, 15 August 2011
PhoP-PhoQ is a two-component system which governs virulence and mediates the adptation to Mg+2-limiting conditions. PhoP is a response regulator and PhoQ is the inner membrane sensor. See details on PhoP in PhoP Regulatory Domain.
3D Structures of PhoP-PhoQ3D Structures of PhoP-PhoQ
PhoPPhoP
3r0j – MtPhoP – Mycobacterium tuberculosis
2pmu – MtPhoP DNA-binding domain
2pkx – EcPhoP regulatory domain (mutant) – Escherichia coli
2pl1 - EcPhoP regulatory domain (mutant) + BeF3
1mvo – PhoP N terminal – Bacillus subtilis
PhoQPhoQ
3cgy – StPhoQ catalytic domain + radicicol – Salmonella typhimurium
3cgz - StPhoQ catalytic domain
1yax - StPhoQ sensor domain (mutant)
3bq8 – EcPhoQ
3bqa – EcPhoQ (mutant)
1id0 – EcPhoQ kinase domain