Ribonucleotide reductase: Difference between revisions
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{{STRUCTURE_2xo4| PDB=2xo4 | SIZE=400| SCENE= |right|CAPTION=Ribonucleotide from ''E. coli'' small | {{STRUCTURE_2xo4| PDB=2xo4 | SIZE=400| SCENE= |right|CAPTION=Ribonucleotide from ''E. coli'' large subunit and small subunit peptide, [[2xo4]] }} | ||
'''Ribonucleotide reductase''' (RNR) catalyzes the formation of deoxyribonucleotides from ribonucleotides. The RNR is a tetramer composed from large (RNR1) and small (RNR2) subunits. Thymidine triphosphate (TTP) is an effector in the reaction. | '''Ribonucleotide reductase''' (RNR) catalyzes the formation of deoxyribonucleotides from ribonucleotides. The RNR is a tetramer composed from large (RNR1) and small (RNR2) subunits. Thymidine triphosphate (TTP) is an effector in the reaction. | ||
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[[1zyz]], [[1zzd]], [[2cvs]], [[2cvt]], [[2cvu]], [[2cvv]], [[2cvw]], [[2cvx]], [[2cvy]] - yRNR R1 – yeast<BR /> | [[1zyz]], [[1zzd]], [[2cvs]], [[2cvt]], [[2cvu]], [[2cvv]], [[2cvw]], [[2cvx]], [[2cvy]] - yRNR R1 – yeast<BR /> | ||
[[1pem]] - StRNR R1 - Salmonella typhimurium<BR /> | [[1pem]] - StRNR R1 - ''Salmonella typhimurium''<BR /> | ||
[[5r1r]], [[6r1r]], [[7r1r]], [[1r1r]], [[1rlr]], [[1mrr]] - EcRNR R1 – Escherichia coli | [[5r1r]], [[6r1r]], [[7r1r]], [[1r1r]], [[1rlr]], [[1mrr]] - EcRNR R1 – ''Escherichia coli'' | ||
===RNR large subunit complex=== | ===RNR large subunit complex=== | ||
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[[1yfd]], [[1piz]], [[1pj0]], [[1pj1]], [[1pm2]], [[1pim]], [[1piu]], [[1biq]], [[2av8]], [[1pfr]] - EcRNR R2 (mutant) <BR /> | [[1yfd]], [[1piz]], [[1pj0]], [[1pj1]], [[1pm2]], [[1pim]], [[1piu]], [[1biq]], [[2av8]], [[1pfr]] - EcRNR R2 (mutant) <BR /> | ||
[[3hf1]], [[2vux]], [[2uw2]] – hRNR M2<BR /> | [[3hf1]], [[2vux]], [[2uw2]] – hRNR M2<BR /> | ||
[[3mjo]], [[3dhz]], [[1oqu]], [[1kgn]], [[1kgo]], [[1kgp]] – RNR R2 – Corynebacterium ammoniagenes<BR /> | [[3mjo]], [[3dhz]], [[1oqu]], [[1kgn]], [[1kgo]], [[1kgp]] – RNR R2 – ''Corynebacterium ammoniagenes''<BR /> | ||
[[2p1i]] – RNR R2 – Plasmodium yoelii<BR /> | [[2p1i]] – RNR R2 – ''Plasmodium yoelii''<BR /> | ||
[[2o1z]] - RNR R2 – Plasmodium vivax<BR /> | [[2o1z]] - RNR R2 – ''Plasmodium vivax''<BR /> | ||
[[1w68]], [[1h0n]], [[1h0o]], [[1xsm]] – mRNR R2 – mouse<BR /> | [[1w68]], [[1h0n]], [[1h0o]], [[1xsm]] – mRNR R2 – mouse<BR /> | ||
[[1smq]], [[1sms]] – yRNR 2<BR /> | [[1smq]], [[1sms]] – yRNR 2<BR /> | ||
[[1syy]] - CtRNR R2 – Chlamydia trachomatis<BR /> | [[1syy]] - CtRNR R2 – ''Chlamydia trachomatis''<BR /> | ||
[[2ani]] - CtRNR R2 (mutant) <BR /> | [[2ani]] - CtRNR R2 (mutant) <BR /> | ||
[[1uz]]r – RNR R2 – Mycobacterium tuberculosis<BR /> | [[1uz]]r – RNR R2 – ''Mycobacterium tuberculosis''<BR /> | ||
[[1r2f]] - StRNR R2 | [[1r2f]] - StRNR R2 | ||
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===RNR small+large subunit=== | ===RNR small+large subunit=== | ||
[[ | [[2xak]], [[2xap]], [[2xo4]], [[2xo5]] - EcRNR R1+ R2 peptide<BR /> | ||
[[ | |||
[[2xav]], [[2xaw]], [[2xax]], [[2xay]], [[2xaz]], [[2x0x]] - EcRNR R1 (mutant) + R2 peptide<BR /> | [[2xav]], [[2xaw]], [[2xax]], [[2xay]], [[2xaz]], [[2x0x]] - EcRNR R1 (mutant) + R2 peptide<BR /> | ||
[[2bq1]] - StRNR R1+ R2 | [[2bq1]] - StRNR R1+ R2 | ||
[[1xjf]] – TmRNR + ATP – Thermotoga maritima<BR /> | [[1xjf]] – TmRNR + ATP – ''Thermotoga maritima''<BR /> | ||
[[1xjg]] - TmRNR + ATP-UDP<BR /> | [[1xjg]] - TmRNR + ATP-UDP<BR /> | ||
[[1xjj]] - TmRNR + GTP<BR /> | [[1xjj]] - TmRNR + GTP<BR /> | ||