1bhn: Difference between revisions
New page: left|200px<br /> <applet load="1bhn" size="450" color="white" frame="true" align="right" spinBox="true" caption="1bhn, resolution 2.4Å" /> '''NUCLEOSIDE DIPHOSPHA... |
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==About this Structure== | ==About this Structure== | ||
1BHN is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]] with 35G as [[http://en.wikipedia.org/wiki/ligand ligand]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.6 2.7.4.6]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1BHN OCA]]. | 1BHN is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]] with 35G as [[http://en.wikipedia.org/wiki/ligand ligand]]. Active as [[http://en.wikipedia.org/wiki/Nucleoside-diphosphate_kinase Nucleoside-diphosphate kinase]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.6 2.7.4.6]]. Structure known Active Site: . Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1BHN OCA]]. | ||
==Reference== | ==Reference== | ||
The three-dimensional structures of two isoforms of nucleoside diphosphate kinase from bovine retina., Ladner JE, Abdulaev NG, Kakuev DL, Tordova M, Ridge KD, Gilliland GL, Acta Crystallogr D Biol Crystallogr. 1999 Jun;55(Pt 6):1127-35. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10329774 10329774] | The three-dimensional structures of two isoforms of nucleoside diphosphate kinase from bovine retina., Ladner JE, Abdulaev NG, Kakuev DL, Tordova M, Ridge KD, Gilliland GL, Acta Crystallogr D Biol Crystallogr. 1999 Jun;55(Pt 6):1127-35. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10329774 10329774] | ||
[[Category: Bos taurus]] | [[Category: Bos taurus]] | ||
[[Category: Nucleoside-diphosphate kinase]] | |||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Abdulaev, N.G.]] | [[Category: Abdulaev, N.G.]] | ||
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[[Category: phosphotransferase]] | [[Category: phosphotransferase]] | ||
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Revision as of 13:16, 30 October 2007
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NUCLEOSIDE DIPHOSPHATE KINASE ISOFORM A FROM BOVINE RETINA
OverviewOverview
The crystal structures of two isoforms of nucleoside diphosphate kinase, from bovine retina overexpressed in Escherischia coli have been determined, to 2.4 A resolution. Both the isoforms, NBR-A and NBR-B, are hexameric and, the fold of the monomer is in agreement with NDP-kinase structures from, other biological sources. Although the polypeptide chains of the two, isoforms differ by only two residues, they crystallize in different space, groups. NBR-A crystallizes in space group P212121 with an entire hexamer, in the asymmetric unit, while NBR-B crystallizes in space group P43212, with a trimer in the asymmetric unit. The highly conserved, nucleotide-binding site observed in other nucleoside diphosphate kinase, structures is also observed here. Both NBR-A and NBR-B were crystallized, in ... [(full description)]
About this StructureAbout this Structure
1BHN is a [Single protein] structure of sequence from [Bos taurus] with 35G as [ligand]. Active as [Nucleoside-diphosphate kinase], with EC number [2.7.4.6]. Structure known Active Site: . Full crystallographic information is available from [OCA].
ReferenceReference
The three-dimensional structures of two isoforms of nucleoside diphosphate kinase from bovine retina., Ladner JE, Abdulaev NG, Kakuev DL, Tordova M, Ridge KD, Gilliland GL, Acta Crystallogr D Biol Crystallogr. 1999 Jun;55(Pt 6):1127-35. PMID:10329774
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