User:Stephen Mills/Peptide tutorial 1: Difference between revisions

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Identify the α-carbons on each amino acid.
Identify the α-carbons on each amino acid.


<Structure load='Arginine.pdb' size='250' frame='true' align='left' caption='Arginine' scene='User:Stephen_Mills/Sandbox_2_Peptide_tutorial/Arginine/3' />
<Structure load='Arginine.pdb' size='300' frame='true' align='left' caption='Arginine' scene='User:Stephen_Mills/Sandbox_2_Peptide_tutorial/Arginine/3' />
<Structure load='Tyrosine.pdb' size='250' frame='true' align='right' caption='Tyrosine' scene='User:Stephen_Mills/Sandbox_2_Peptide_tutorial/Tyrosine/1' />
<Structure load='Tyrosine.pdb' size='300' frame='true' align='right' caption='Tyrosine' scene='User:Stephen_Mills/Sandbox_2_Peptide_tutorial/Tyrosine/1' />


Click <scene name='User:Stephen_Mills/Sandbox_2_Peptide_tutorial/Argininealpha/1'>here</scene> to label the α-carbon on Arginine
Click <scene name='User:Stephen_Mills/Sandbox_2_Peptide_tutorial/Argininealpha/1'>here</scene> to label the α-carbon on Arginine
Clich <scene name='User:Stephen_Mills/Sandbox_2_Peptide_tutorial/Tyrosinealpha/1'>here</scene> to label the α-carbon on Tyrosine
Click <scene name='User:Stephen_Mills/Sandbox_2_Peptide_tutorial/Tyrosinealpha/1'>here</scene> to label the α-carbon on Tyrosine

Revision as of 00:39, 25 July 2011

Biochemistry Tutorial #1 - PeptidesBiochemistry Tutorial #1 - Peptides

The alpha amino acids polymerize, or bond, through the elimination of a water molecule. Polymers composed of two amino acid residues are known as dipeptides. Longer polymers are called oligopeptides (up to around 20 amino acids) or polypeptides (> 20 amino acids). Proteins can contain any number of amino acids linked together but each has a unique length (number of amino acids) and sequence (the identity and order of amino acids in the polymer).

In this excercise, you will identify amino acids, the amino and carboxy groups involved in the peptide bond, look at peptide bonds and oligopeptide structure and finally also examine disulfide bonds.

Which amino acid is this?Which amino acid is this?

Drag the structure with the mouse to rotate

Scroll down when you know what it is.

You can rotate the amino acid by holding down the right mouse button and dragging.





















Drag the structure with the mouse to rotate





This is Arginine (Arg, R) and amino acid with a positively charged side chain.

Identify the α-amino and α-carboxy groups involved in peptide bond formation.


Click to see the N and C groups labelled.











Drag the structure with the mouse to rotate


Name the new amino acid.Name the new amino acid.

Scroll down to get the answer























Drag the structure with the mouse to rotate

This is Tyrosine (Tyr, Y), an aromatic amino acid

Again, identify the amino and carboxy groups involved in peptide bond formation.

Click to have the N and C groups labeled.















Now here are both structures. Identify the α-carbons on each amino acid.

Arginine

Drag the structure with the mouse to rotate

Tyrosine

Drag the structure with the mouse to rotate

Click to label the α-carbon on Arginine Click to label the α-carbon on Tyrosine