3qlw: Difference between revisions
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===Candida albicans dihydrofolate reductase complexed with NADPH and 5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-ethylpyrimidine-2,4-diamine (UCP120B)=== | |||
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{{ABSTRACT_PUBMED_21726415}} | |||
==About this Structure== | |||
[[3qlw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Candida_albicans Candida albicans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QLW OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:021726415</ref><references group="xtra"/> | |||
[[Category: Candida albicans]] | |||
[[Category: Anderson, A C.]] | |||
[[Category: Bendel, S D.]] | |||
[[Category: Paulsen, J L.]] | |||
[[Category: Antifungal agent]] | |||
[[Category: Candida albican]] | |||
[[Category: Drug design]] | |||
[[Category: Enzyme inhibitor]] | |||
[[Category: Fungal protein]] | |||
[[Category: Model]] | |||
[[Category: Molecular structure]] | |||
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]] | |||
[[Category: Structure-activity relationship]] | |||
[[Category: Tetrahydrofolate dehydrogenase]] | |||
Revision as of 09:44, 20 July 2011
Candida albicans dihydrofolate reductase complexed with NADPH and 5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-ethylpyrimidine-2,4-diamine (UCP120B)Candida albicans dihydrofolate reductase complexed with NADPH and 5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-ethylpyrimidine-2,4-diamine (UCP120B)
Template:ABSTRACT PUBMED 21726415
About this StructureAbout this Structure
3qlw is a 2 chain structure with sequence from Candida albicans. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Paulsen JL, Bendel SD, Anderson AC. Crystal structures of Candida albicans dihydrofolate reductase bound to propargyl-linked antifolates reveal the flexibility of active site loop residues critical for ligand potency and selectivity. Chem Biol Drug Des. 2011 Jul 5. doi: 10.1111/j.1747-0285.2011.01169.x. PMID:21726415 doi:10.1111/j.1747-0285.2011.01169.x