Group:MUZIC:Myopodin: Difference between revisions
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==Pathology== | ==Pathology== | ||
Already in 2001 Lin et al showed that ''SYNPO2'' gene exhibit frequently delations in aggresive prostata cancer <ref> PMID:11696420</ref>. Later analysis gave the evidence that Myopodin plays an important role as tumor suppressor, considering that in normal urothelium of the bladder Myopodin is localized in the cytoplasm and in the nucleus, however in mutated tissue of superficial and invasive tumor is observed a reduced nuclear expression of Myopodin <ref> PMID:12917631 </ref>. | Already in 2001 Lin et al showed that ''SYNPO2'' gene exhibit frequently delations in aggresive prostata cancer <ref> PMID:11696420</ref>. Later analysis gave the evidence that Myopodin plays an important role as tumor suppressor, considering that in normal urothelium of the bladder Myopodin is localized in the cytoplasm and in the nucleus, however in mutated tissue of superficial and invasive bladder tumor is observed a reduced nuclear expression of Myopodin <ref> PMID:12917631 </ref>. | ||
==References== | ==References== | ||
<references/> | <references/> | ||