Hexokinase: Difference between revisions
Michal Harel (talk | contribs) No edit summary |
Michal Harel (talk | contribs) No edit summary |
||
| Line 28: | Line 28: | ||
G6P inhibits hexokinase by binding to the N-terminal domain(this is simple feedback inhibition). It competitively inhibits the binding of ATP [8]. If the cell is not using the G6P that it is making, then it stops making it. In this way, hexokinase can also slow down glycolysis. Hexokinase I is thought to be the "pacemaker" of glycolysis in brain tissue and red blood cells [4]. Inorganic phosphate allosterically relieves hexokinase of inhibition by G6P [8]. | G6P inhibits hexokinase by binding to the N-terminal domain(this is simple feedback inhibition). It competitively inhibits the binding of ATP [8]. If the cell is not using the G6P that it is making, then it stops making it. In this way, hexokinase can also slow down glycolysis. Hexokinase I is thought to be the "pacemaker" of glycolysis in brain tissue and red blood cells [4]. Inorganic phosphate allosterically relieves hexokinase of inhibition by G6P [8]. | ||
==3D structures of hexokinase== | |||
==Additional Resources== | ==Additional Resources== | ||