Triose Phosphate Isomerase: Difference between revisions

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 == Mechanism ==
-TPI catalyzes the transfer of a hydrogen atom from carbon 1 to carbon 2, an intramolecular oxidation-reduction reaction.[[Image:TPI 2D mechanism2.png|right|thumb|400px| '''Isomerization reaction catalyzed by TPI''']] This isomerization of a ketose to an aldose proceeds through an ''cis''-enediol(ate) intermediate. This isomerization proceeds without any cofactors and the enzyme confers a 10<sup>9</sup> rate enhancement relative to the nonenzymatic reaction involving a chemical base (acetate ion)<ref>PMID:2043623</ref>.
+TPI catalyzes the transfer of a hydrogen atom from carbon 1 to carbon 2, an intramolecular oxidation-reduction reaction This isomerization of a ketose to an aldose proceeds through an ''cis''-enediol(ate) intermediate. This isomerization proceeds without any cofactors and the enzyme confers a 10<sup>9</sup> rate enhancement relative to the nonenzymatic reaction involving a chemical base (acetate ion)<ref>PMID:2043623</ref>.
+{|[[Image:TPI 2D mechanism2.png|right|thumb|400px| '''Isomerization reaction catalyzed by TPI''']]
+|-
 [[Image:TPIkinetics.png|thumb|400px| '''Kinetic constants of Triose Phosphate Isomerase''']]
+|}