Flavodoxin: Difference between revisions

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[[Image:2bmv.png|left|200px|thumb|Crystal Structure of Flavodoxin, [[2bmv]]]]
[[Image:2bmv.png|left|200px|thumb|Crystal Structure of Flavodoxin, [[2bmv]]]]
{{STRUCTURE_2bmv|  PDB=2bmv  | SIZE=300| SCENE=Flavodoxin/Cv/1 |right|CAPTION=Apo-Flavodoxin from ''Helicobacter pylori'', [[2bmv]] }}
{{STRUCTURE_2bmv|  PDB=2bmv  | SIZE=300| SCENE=Flavodoxin/Cv/1 |right|CAPTION=Apo-Flavodoxin from ''Helicobacter pylori'' complexed with benzamidine and chloride ion, [[2bmv]] }}


[[Flavodoxin]] (FDX) is a bacterial protein which contains flavin mononucleotide (FMN) or flavin adenine dinucleotide (FAD).  It participates in nitrogen metabolism and reduces N2 to NH3 while changing from its oxidized quinone state FDX-ox via semiquinone FDX-sq to its reduced hydroquinone state FDX-red.  '''NrdI''' is a FDX which is involved in ribonucleotide reduction.  '''WrbA (Tryptophan Repressor-Binding Protein)''' is also FDX.  In ''E. coli'' there are 2 distinct FDX I and II. The images at the left and at the right correspond to one representative FDX structure, ''i.e.'' the crystal structure of apo-flavodoxin from ''Helicobacter pylori'' ([[2bmv]]).  The space filling objects are of chloride ion and benzamidine.
[[Flavodoxin]] (FDX) is a bacterial protein which contains flavin mononucleotide (FMN) or flavin adenine dinucleotide (FAD).  It participates in nitrogen metabolism and reduces N2 to NH3 while changing from its oxidized quinone state FDX-ox via semiquinone FDX-sq to its reduced hydroquinone state FDX-red.  '''NrdI''' is a FDX which is involved in ribonucleotide reduction.  '''WrbA (Tryptophan Repressor-Binding Protein)''' is also FDX.  In ''E. coli'' there are 2 distinct FDX I and II. The images at the left and at the right correspond to one representative FDX structure, ''i.e.'' the crystal structure of apo-flavodoxin from ''Helicobacter pylori'' ([[2bmv]]).  The space filling objects are of chloride ion and benzamidine.

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Alexander Berchansky, Michal Harel, Jaime Prilusky