Peroxisome Proliferator-Activated Receptors: Difference between revisions
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==Natural Ligands== | ==Natural Ligands== | ||
[[Image: Linoleic_Acid.png| | [[Image: Linoleic_Acid.png|150px|left|thumb| PPARγ Ligand, Linoleic Acid]] | ||
PPAR gamma binds polyunsaturated fatty acids like linoleic acid, linolenic acid, and eicosapentaenoic acid at affinities that are in line with serum levels found in the blood. PPARα binds a variety of saturated and unsaturated fatty acids including palmitic acid, oleic acid, linoleic acid, and arachidonic acid.<ref>PMID:1316614</ref> PPARδs ligand selectivity is intermediate between that of the other isotypes and is activated by palmitic acid and a number of eicosanoids.<ref>PMID:7836471</ref> | |||
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