User:Luis E Ramirez-Tapia/Sandbox 3: Difference between revisions

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===Understanding the morph===

This morph was produced using a energy minimization morphing software (Yale Morph), the structures were the INITIATION (PDB ID: 1qln) and the INTERMIDATE STATE (PDB ID: 3e2e) complexes.

One of the most striking characteristics of this enzyme is the HUGE conformational change of the N-terminus part of the enzyme, the Subdomain H (alfa-helices in green) and the helices C1-C2. Recently a new structure from an intermediate state (PDB ID:3e2e) was resolved(1). You can see the transition between the <scene name='User:Luis_E_Ramirez-Tapia/Sandbox_3/Initiation/2'>INITIATION</scene> conformation and the <scene name='User:Luis_E_Ramirez-Tapia/Sandbox_3/Intermediate_state/4'>INTERMEDIATE STATE</scene> complex by pressing the follow button.

One of the most striking characteristics of this enzyme is the HUGE conformational change of the N-terminus part of the enzyme, the Subdomain H (alfa-helices in green) and the helices C1-C2. Recently a new structure from an intermediate state (PDB ID:3e2e) was resolved [http://www.ncbi.nlm.nih.gov/pubmed/18948533 (1)]. You can see the transition between the <scene name='User:Luis_E_Ramirez-Tapia/Sandbox_3/Initiation/2'>INITIATION</scene> conformation and the <scene name='User:Luis_E_Ramirez-Tapia/Sandbox_3/Intermediate_state/4'>INTERMEDIATE STATE</scene> complex by pressing the follow button.

<jmol>

@@ Line 24: / Line 24: @@
 ===Understanding the morph===
 This morph was produced using a energy minimization morphing software (Yale Morph), the structures were the  INITIATION (PDB ID: 1qln) and the INTERMIDATE STATE (PDB ID: 3e2e) complexes.
-One of the most striking characteristics of this enzyme is the<b> HUGE conformational change</b> of the <font color='magenta'>N-terminus part of the enzyme</font>, the <font color ="green">Subdomain H</font> (alfa-helices in green) and the <font color='orange'>helices C1-C2</font>. Recently a new structure from an intermediate state (PDB ID:3e2e) was resolved(1). You can see the transition between the <scene name='User:Luis_E_Ramirez-Tapia/Sandbox_3/Initiation/2'>INITIATION</scene> conformation and the <scene name='User:Luis_E_Ramirez-Tapia/Sandbox_3/Intermediate_state/4'>INTERMEDIATE STATE</scene> complex by pressing the follow button.
+One of the most striking characteristics of this enzyme is the<b> HUGE conformational change</b> of the <font color='magenta'>N-terminus part of the enzyme</font>, the <font color ="green">Subdomain H</font> (alfa-helices in green) and the <font color='orange'>helices C1-C2</font>. Recently a new structure from an intermediate state (PDB ID:3e2e) was resolved [http://www.ncbi.nlm.nih.gov/pubmed/18948533 (1)]. You can see the transition between the <scene name='User:Luis_E_Ramirez-Tapia/Sandbox_3/Initiation/2'>INITIATION</scene> conformation and the <scene name='User:Luis_E_Ramirez-Tapia/Sandbox_3/Intermediate_state/4'>INTERMEDIATE STATE</scene> complex by pressing the follow button.
 <jmol>
 <jmolButton>