Tol: Difference between revisions

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 ===Interaction of Tol with Colicins===
 <structure load='2ivz' size='300' align='right' caption='Interaction of TolB and Colicin E9' (PDB entry [[2ivz]]  |  SCENE= Tol/Tolbcol/1 />
-The name 'Tol' derives from experiments which show that the ''tol'' mutant is tolerant to colicin action<ref name='Davies'>PMID: 1095546</ref>.
+It is interesting to note that the name 'Tol' derives from experiments which show that the ''tol'' mutant is tolerant to colicin action<ref name='Davies'>PMID: 1095546</ref>.
 The Tol-Pal system is used by group A colicins in order to translocate across the outer membrane, targeting mainly the inner membrane component TolA as well as TolQ and TolR.  The colicins set up a translocon, constituting of the outer membrane receptor, translocator proteins and one or more periplasmic translocator proteins.  The colicins recruit the Tol proteins using a Tol binding antigen, or epitope, which is embedded in the IUTD (Intrinsically Unstructured [[Translocation domain]]) found on the N-terminal (T-) domain of the colicin<ref>PMID: 21060316</ref>.