YbgF: Difference between revisions
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
[[Image:YbgF.jpg|400px|right|thumb| YbgF<ref name='Gerding'>PMID: 17233825</ref> ]] | |||
YbgF is a periplasmic protein which interacts with the C-terminal domain of TolA (TolAIII) during the import of colicin A into the cytoplasm. <ref>PMID: 11994151</ref> | YbgF is a periplasmic protein which interacts with the C-terminal domain of TolA (TolAIII) during the import of colicin A into the cytoplasm. <ref>PMID: 11994151</ref> | ||
==Structure== | ==Structure== | ||
YbgF is a periplasmic protein with an N-terminal coiled coil domain (NTD) (''see'' 3D structure 2XEV) and a C-terminal tetratricopeptide domain (TPR), both of which are autonomous<ref name='Gerding'>PMID: 17233825</ref>. As seen in the 3D structure 2WZ7, the NTD forms an elongated trimer which is connected via a flexible linker to the TPR trimer. This connection can be cleaved by proteases<ref name='Krachler'>PMID: 20816983</ref>. | |||
{{STRUCTURE_2wz7 | PDB=2wz7 | SCENE= YbgF/Ybgf/1 }} | {{STRUCTURE_2wz7 | PDB=2wz7 | SCENE= YbgF/Ybgf/1 }} | ||
==Function== | |||
{{STRUCTURE_2xev | PDB=2xev | SCENE= YbgF/Ntermygbf/1 }} | {{STRUCTURE_2xev | PDB=2xev | SCENE= YbgF/Ntermygbf/1 }} | ||
| Line 8: | Line 15: | ||
==References== | ==References== | ||
<references/> | <references/> | ||
NTD TPR | |||