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Samantha Stone Sandbox: Difference between revisions

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Its structure consists of ATP, adenosine 5'-(beta,gamma-methylene)triphosphate (AMPPCP), and cyclopiazonic acid (CZA). A metal (Mg or Mn) must react in the ATP binding site for CZA to bind and react. This occurs at the M1 helix. Knowing the structure of the binding site allows for drugs that can be designed to target this ATPase.  
Its structure consists of ATP, adenosine 5'-(beta,gamma-methylene)triphosphate (AMPPCP), and cyclopiazonic acid (CZA). A metal (Mg or Mn) must react in the ATP binding site for CZA to bind and react. This occurs at the M1 helix. Knowing the structure of the binding site allows for drugs that can be designed to target this ATPase.  


{{STRUCTURE_3cin |  PDB=3cin |  SCENE=  }}
{{STRUCTURE_3fpb |  PDB=3fpb |  SCENE=  }}


<scene name='Samantha_Stone_Sandbox/Mg_ii_binding_site/2'>Full Molecule</scene>
<scene name='Samantha_Stone_Sandbox/Mg_ii_binding_site/2'>Full Molecule</scene>

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Samantha Stone, Karsten Theis
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