Sandbox Reserved 200: Difference between revisions

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==Dimers==
==Dimers==
<Structure load='1A2W' size='400' frame='true' align='right' caption='Ribonuclease A Dimer' scene='Sandbox_Reserved_200/Minor_dimer/2' />
<Structure load='1A2W' size='400' frame='true' align='right' caption='Ribonuclease A Dimer' scene='Sandbox_Reserved_200/Minor_dimer/4' />
Ribonuclease A has both a <scene name='Sandbox_Reserved_200/Major_dimer/11'>major</scene> and <scene name='Sandbox_Reserved_200/Minor_dimer/4'>minor</scene> dimer which are very similar to one another. Though they are similar, they are formed by different types of 3D domain swapping.  3D domain swapping occurs when identical domains are interchanged.  The major dimer is formed by 3D domain swapping the β-strand of the C-terminus.<ref name="liu98"/> The minor dimer, on the other hand, is formed by 3D domain swapping of its α-helix of the N-terminus <ref name="liu98"/>.  Domain swapping is extremely specific and can only occur at the <scene name='Sandbox_Reserved_200/Major_dimer/10'>C-terminus</scene> or the <scene name='Sandbox_Reserved_200/Major_dimer/9'>N-terminus</scene>.
Ribonuclease A has both a <scene name='Sandbox_Reserved_200/Major_dimer/11'>major</scene> and <scene name='Sandbox_Reserved_200/Minor_dimer/4'>minor</scene> dimer which are very similar to one another. Though they are similar, they are formed by different types of 3D domain swapping.  3D domain swapping occurs when identical domains are interchanged.  The major dimer is formed by 3D domain swapping the β-strand of the C-terminus.<ref name="liu98"/> The minor dimer, on the other hand, is formed by 3D domain swapping of its α-helix of the N-terminus <ref name="liu98"/>.  Domain swapping is extremely specific and can only occur at the <scene name='Sandbox_Reserved_200/Major_dimer/10'>C-terminus</scene> or the <scene name='Sandbox_Reserved_200/Major_dimer/9'>N-terminus</scene>.


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OCA, Lexi Gehring, R. Jeremy Johnson, Jaime Prilusky