Sandbox Reserved 313: Difference between revisions

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 ''Neutral Mg2+-independent sphingomyelinases'' - Thee activities of magnesium independent nSMase are found predominantly in the cytosol and are not very well known<ref name="gp3">PMID: 12401200 </ref>.
-''Alkaline sphingomyelinase (bSMase)'' - Alkaline bSMase is found in the intestine and hydrolyses sphingomyelin in both the lumen and the mucosal membrane and requires bile salts for activity. This enzyme shares some similarities with the nucleotide pyrophosphatase(NPP) family and is called NPP7.  The enzyme has a hydrophobic domain at the N and C terminus, where the N terminus acts as a signal peptide (which is eventually cleaved) and the C terminus acts as a signal anchor which attaches the enzyme to membranes<ref name="gp3">PMID: 12401200 </ref><ref name="gp8">PMID: 16631405 </ref>.
+''Alkaline sphingomyelinase (bSMase)'' - Alkaline SMase is found in the intestine and hydrolyses sphingomyelin in both the lumen and the mucosal membrane and requires bile salts for activity. This enzyme shares some similarities with the nucleotide pyrophosphatase(NPP) family and is called NPP7.  The enzyme has a hydrophobic domain at the N and C terminus, where the N terminus acts as a signal peptide (which is eventually cleaved) and the C terminus acts as a signal anchor which attaches the enzyme to membranes<ref name="gp3">PMID: 12401200 </ref><ref name="gp8">PMID: 16631405 </ref>.
-.
 ''Bacterial sphingomyelinase'' -