Sandbox Reserved 344: Difference between revisions
No edit summary |
No edit summary |
||
| Line 34: | Line 34: | ||
The PhoP/PhoQ system may also be found in non-cytoplasmic pathogens, such as ''Erwinia carotovora supsb. carotovora'', a plant pathogen living in the intercellular fluid, or non-pathogenic bacteria. <ref name = "Groisman"/> | The PhoP/PhoQ system may also be found in non-cytoplasmic pathogens, such as ''Erwinia carotovora supsb. carotovora'', a plant pathogen living in the intercellular fluid, or non-pathogenic bacteria. <ref name = "Groisman"/> | ||
=Importance of PhoP= | =Importance of PhoP= | ||
PhoP/PhoQ plays in key role in certain bacteria becoming virulent. For example, ''Salmonella typhimurium'' becomes avirulent when it carries a phoP mutation.<ref name = "Groisman1989"> PMID: | PhoP/PhoQ plays in key role in certain bacteria becoming virulent. For example, ''Salmonella typhimurium'' becomes avirulent when it carries a phoP mutation.<ref name = "Groisman1989"> PMID:2674945</ref> This makes it a promising target for vaccine and antimicrobial drug development. | ||
=References= | =References= | ||
<references/> | <references/> | ||