Sandbox Reserved 316: Difference between revisions

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Revision as of 04:17, 4 April 2011 view source Eric Ginter (talk \| contribs) 89 edits No edit summary ← Older edit		Revision as of 04:18, 4 April 2011 view source Eric Ginter (talk \| contribs) 89 edits No edit summary Newer edit →
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	This enzyme is isolated from the natural product biosynthetic pathways of ''Aspergillus terreus'', specifically the polyketide biosynthetic pathway. Simvastatin Synthase converts the inactive monacolin J acid (<scene name='Sandbox_Reserved_316/Blah/3'>MJA</scene>) by dimethylbutyryl chloride to yield the protected form of simvastatin (Figure 2), which subsequently undergoes lactonization to yield simvastatin<ref name="paper5">PMID:19875080</ref>.		This enzyme is isolated from the natural product biosynthetic pathways of ''Aspergillus terreus'', specifically the polyketide biosynthetic pathway. Simvastatin Synthase converts the inactive monacolin J acid (<scene name='Sandbox_Reserved_316/Blah/3'>MJA</scene>) by dimethylbutyryl chloride to yield the protected form of simvastatin (Figure 2), which subsequently undergoes lactonization to yield simvastatin<ref name="paper5">PMID:19875080</ref>.

	[[Image:Sim_mja.jpg]]		[[Image:Sim_mja.jpg]]