Sandbox Reserved 327: Difference between revisions
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<scene name='Sandbox_Reserved_327/Ribbon_structure/1'>Ribbon Structure</scene> | <scene name='Sandbox_Reserved_327/Ribbon_structure/1'>Ribbon Structure</scene> | ||
*encoded by ''SUI1'' | *encoded by ''SUI1'' | ||
*regulator of start site selection | |||
*possible figure: show where eIF1 located in the ribosome | *possible figure: show where eIF1 located in the ribosome | ||
==Start Codon Selection (AUG selection)== | |||
stimulates the recruitment of TC to the 40s subunit | |||
==Formation of Multifactor Complex (MFC)== | |||
* | |||
=Mechanism= | =Mechanism= | ||
==binding to the ribosome== | |||
how its bind | how its bind | ||
==binding to the eIF5== | |||
*possible green link: show binding region of eIF1 to the eIF5 --> surface representation | *possible green link: show binding region of eIF1 to the eIF5 --> surface representation | ||
<scene name='Sandbox_Reserved_327/Basic_eif1/3'>eIF5 binding site</scene> | <scene name='Sandbox_Reserved_327/Basic_eif1/3'>eIF5 binding site</scene> | ||
*possible figure: assembly with eIF5 | |||
=how it's released after AUG recognition?= | |||
how it's released after AUG recognition | |||
*possible figure: the release of eIF1 | *possible figure: the release of eIF1 | ||
=Mutations= | =Mutations= | ||
==at the eIF1-eIF5 binding site== | |||
*altering the basic part of eIF1-KH | *altering the basic part of eIF1-KH | ||
*altering the hydrophobic residues of eIF1 | *altering the hydrophobic residues of eIF1 | ||
==others?== | |||
=References= | =References= | ||
<ref name="eIF1"> PMID:17974565 </ref> | <ref name="eIF1"> PMID:17974565 </ref> | ||