Sandbox Reserved 342: Difference between revisions
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XGPRT is a tetramer<ref name="Vos"/>. | XGPRT is a tetramer<ref name="Vos"/>. | ||
PRTase structures fall into two groups, type I and Type II<ref name="Vos"/>. | PRTase structures fall into two groups, type I and Type II<ref name="Vos"/>. | ||
XGTPase has a conserved sequence,85-IVIDDLVDTG-94, which is called the PRib-PP (5-phospho-a-D-ribosyl-1-pyrophosphate)<scene name='Sandbox_Reserved_342/Prib-pp_binding_site/2'>binding site</scene><ref name="Vos"/>. This binding site features two adjacent acidic residues, which are surrounded by hydrophobic residues<ref name="Vos"/>. There is a five-stranded b-sheet surrounded by three or four a-helices that creates a conserved structural core containing the PRib-PP binding site<ref name="Vos"/>. Another region of the sequence in XGTPase forms a lobe, which is involved in substrate recognition<ref name="Vos"/>. | XGTPase has a conserved sequence,85-IVIDDLVDTG-94, which is called the PRib-PP (5-phospho-a-D-ribosyl-1-pyrophosphate)<scene name='Sandbox_Reserved_342/Prib-pp_binding_site/2'>binding site</scene><ref name="Vos"/>(The binding sites of each subunit is shown in pink). This binding site features two adjacent acidic residues, which are surrounded by hydrophobic residues<ref name="Vos"/>. There is a five-stranded b-sheet surrounded by three or four a-helices that creates a conserved structural core containing the PRib-PP binding site<ref name="Vos"/>. Another region of the sequence in XGTPase forms a lobe, which is involved in substrate recognition<ref name="Vos"/>. | ||
<scene name='Sandbox_Reserved_342/Prib-pp_binding_site/2'>binding site</scene> | <scene name='Sandbox_Reserved_342/Prib-pp_binding_site/2'>binding site</scene> | ||